There are 6 ways to get from Louisville to Hartsville by plane, taxi, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Florence Regional Airport, taxi
best- Fly from Louisville International Airport (SDF) to Florence Regional Airport (FLO)plane SDF - FLO
- Take the taxi from Florence Regional Airport (FLO) to Hartsvilletaxi
5h 53m$152–513Drive 507.7 mi
cheapest- Drive from Louisville to Hartsvillecar 507.7 mi
11h 9m$93–134Bus, taxi via Atlanta
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Camdenbus
- Take the taxi from Camden to Hartsvilletaxi
15h 17m$223–346Fly Louisville International Airport to Charlotte Douglas International Airport, bus, taxi
- Fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT)plane SDF - CLT
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the taxi from Camden to Hartsvilletaxi
7h 13m$228–782Drive to Blue Grass Airport, fly to Charlotte Douglas International Airport, bus, taxi
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Charlotte Douglas International Airport (CLT)plane LEX - CLT
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the taxi from Camden to Hartsvilletaxi
7h 4m$249–898Bus, taxi
- Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus
- Take the bus from Columbus - Mound St to Hurricanebus
- Take the bus from Hurricane to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the taxi from Camden to Hartsvilletaxi
19h 32m$196–362
Louisville International Airport (SDF) to Florence Regional Airport (FLO) flights
Questions & Answers
The cheapest way to get from Louisville to Hartsville is to drive which costs $90 - $140 and takes 11h 9m.
The fastest way to get from Louisville to Hartsville is to fly and taxi which takes 5h 53m and costs $150 - $550.
The distance between Louisville and Hartsville is 469 miles. The road distance is 510.7 miles.
The best way to get from Louisville to Hartsville without a car is to bus and taxi via Atlanta which takes 15h 17m and costs $220 - $350.
It takes approximately 5h 53m to get from Louisville to Hartsville, including transfers.
Yes, the driving distance between Louisville to Hartsville is 511 miles. It takes approximately 11h 9m to drive from Louisville to Hartsville.
There are seven+ hotels available in Hartsville.
What companies run services between Louisville, KY, USA and Hartsville, SC, USA?
There is no direct connection from Louisville to Hartsville. However, you can take the line 02 bus to Louisville International Airport, walk to Louisville International Airport (SDF) airport, fly to Florence Regional Airport (FLO), then take the taxi to Hartsville. Alternatively, you can take the bus to Nashville, take the bus to Atlanta Bus Station, take the bus to Camden, then take the taxi to Hartsville.
- Website
- aa.com
Flights from Louisville International Airport to Florence Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $70–410
Flights from Louisville International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $90–600
Flights from Blue Grass Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $100–700
- Website
- southwest.com
Flights from Louisville International Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–650
- Website
- delta.com
Flights from Blue Grass Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Camden
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $40–70
- Schedules at
- flixbus.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to Columbus - Downtown - Mound St
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- $21–60
- Website
- https://baronsbus.com
Bus from Columbus - Mound St to Hurricane
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $15–55
- Website
- https://baronsbus.com
Bus from Hurricane to Charlotte Bus Station
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $28–75
- Website
- https://baronsbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide








