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How to get fromLouisville to Hyannisby plane, bus, bus (Greyhound), train, car, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Louisville to Hyannis by plane, bus, bus (Greyhound), train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Boston Logan Airport, bus

    best
    1. Fly from Louisville International Airport (SDF) to Boston Logan Airport (BOS)plane plane SDF - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    6h 33m
    $140–643

  2. Fly Louisville International Airport to Theodore Francis Green State Airport, train, bus

    cheapest
    1. Fly from Louisville International Airport (SDF) to Theodore Francis Green State Airport (PVD)plane plane SDF - PVD
    2. Take the train from TF Green Airport to South Stationtrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    10h 30m
    $118–474

  3. Bus

    1. Take the bus from Louisville Bus Station to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Bostonbus bus
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    25h 41m
    $188–300

  4. Bus, train via Toledo

    1. Take the bus from Louisville Bus Station to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    26h 37m
    $275–560

  5. Drive  971.8 mi

    1. Drive from Louisville to Hyanniscar car 971.8 mi
    17h 48m
    $178–257

  6. Bus to Covington, fly to Boston Logan Airport, bus

    1. Take the bus from Louisville to Cincinnatibus bus
    2. Fly from Covington (CVG) to Boston Logan Airport (BOS)plane plane CVG - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    8h 21m
    $460–1,085

  7. Fly Louisville International Airport to Barnstable Municipal Airport

    1. Fly from Louisville International Airport (SDF) to Barnstable Municipal Airport (HYA)plane plane SDF - HYA
    5h 50m
    $132–703

  8. Bus via New York

    1. Take the bus from Louisville Bus Station to Dayton Trotwood Bus Stationbus bus
    2. Take the bus from Dayton Trotwood Bus Station to New York Midtownbus bus
    3. Take the bus from New York Midtown to Bostonbus bus
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    26h 16m
    $182–284

  9. Bus, train

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    31h 42m
    $345–769

Louisville to Hyannis by bus

Calendar7Weekly Buses
Duration25h 41mAverage Duration
Ticket$188Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Hyannis.ExpandLaunch map view
  • Distance: 910.3 mi
  • Duration: 6h 33m

What companies run services between Louisville, KY, USA and Hyannis, MA, USA?

You can take a bus from Louisville Bus Station to Hyannis Transportation Center via Cleveland Bus Station, Boston, and Boston South Buses in around 25h 41m. Alternatively, Delta, Cape Air, and four other airlines fly from Louisville International Airport (SDF) to Barnstable Municipal Airport (HYA) twice daily.

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