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How to get fromLouisville to Hyannisby plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)

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There are 8 ways to get from Louisville to Hyannis by plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Barnstable Municipal Airport

    best
    1. Fly from Louisville International Airport (SDF) to Barnstable Municipal Airport (HYA)plane plane SDF - HYA
    6h 24m
    $132–703

  2. Fly Louisville International Airport to Boston Logan Airport, bus

    cheapest
    1. Fly from Louisville International Airport (SDF) to Boston Logan Airport (BOS)plane plane SDF - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    6h 43m
    $130–593

  3. Bus via Brentwood

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville, TN to New York, NYbus bus Ny
    3. Take the bus from NYC Downtown to Bostonbus bus
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    27h 41m
    $192–253

  4. Bus, train via Toledo

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis to Toledobus bus
    3. Take the train from Toledo to Bostontrain train
    4. Take the bus from Boston to Hyannisbus bus
    28h
    $488–834

  5. Drive  971.8 mi

    1. Drive from Louisville to Hyanniscar car 971.8 mi
    17h 47m
    $178–257

  6. Drive to Covington, fly to Boston Logan Airport, bus

    1. Drive from Louisville to Covington (CVG)car car
    2. Fly from Covington (CVG) to Boston Logan Airport (BOS)plane plane CVG - BOS
    3. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    6h 45m
    $445–1,265

  7. Bus

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Bostonbus bus
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    30h 14m
    $230–364

  8. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    4. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    32h 29m
    $670–1,079

Louisville to Hyannis by bus, train, and foot

Calendar7Weekly Services
Duration28hAverage Duration
Ticket$488Cheapest Price
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Map of how to get from Louisville to Hyannis.ExpandLaunch map view
  • Distance: 858.6 mi
  • Duration: 6h 24m

What companies run services between Louisville, KY, USA and Hyannis, MA, USA?

American Airlines, United Airlines, and Delta fly from Louisville International Airport (SDF) to Barnstable Municipal Airport (HYA) 3 times a day. Alternatively, you can take a bus from Louisville, KY to Hyannis Transportation Center via Nashville, Fulton Station Outbound, Nashville, TN, New York, NY, NYC Downtown, Boston, and Boston South Buses in around 27h 41m.

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