There are 7 ways to get from Louisville to Illinois by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Chicago Midway International Airport
best- Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane SDF - MDW
3h 19m$59–398Bus
cheapest- Take the bus from Louisville Bus Station to Chicago Bus Stationbus Greyhound US0100
6h$45–75Bus, train
- Take the bus from Louisville Bus Station to Indianapolis Union Stationbus Greyhound US0100 / ...
- Take the train from Indianapolis to Chicago Union Stationtrain Cardinal
7h 55m$73–164Drive 294.4 mi
- Drive from Louisville to Chicagocar 294.4 mi
5h 3m$54–78Fly Louisville International Airport to Chicago O'Hare International Airport
- Fly from Louisville International Airport (SDF) to Chicago O'Hare International Airport (ORD)plane SDF - ORD
3h 46m$54–338Drive to Blue Grass Airport, fly to Chicago O'Hare International Airport
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD)plane LEX - ORD
3h 47m$55–284Bus via Lafayette (Amtrak)
- Take the bus from Louisville, KY to Lafayette Amtrak Stationbus Nashville
- Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus Nashville
7h$58–91
Louisville to Illinois by bus
Comparing Your Travel Options
The cheapest way to get from Louisville to Illinois is to bus which costs $45 - $75 and takes 6h.
The fastest way to get from Louisville to Illinois is to fly which takes 3h 19m and costs $55 - $400.
Yes, there is a direct bus departing from Louisville Bus Station station and arriving at Chicago Bus Station station. Services depart every four hours, and operate every day. The journey takes approximately 6h.
The distance between Louisville and Illinois is 290 miles. The road distance is 296.1 miles.
The best way to get from Louisville to Illinois without a car is to bus which takes 6h and costs $45 - $75.
It takes approximately 3h 19m to get from Louisville to Illinois, including transfers.
Louisville to Illinois bus services, operated by Greyhound USA, depart from Louisville Bus Station.
The best way to get from Louisville to Illinois is to fly which takes 3h 19m and costs $55 - $400. Alternatively, you can bus, which costs $45 - $75 and takes 6h.
Louisville to Illinois bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Illinois is 1h behind Louisville. It is currently 5:16 AM in Louisville and 4:16 AM in Illinois.
What companies run services between Louisville, KY, USA and Illinois, USA?
Southwest Airlines flies from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW) 4 times a day. Alternatively, Greyhound USA operates a bus from Louisville Bus Station to Chicago Bus Station 4 times a day. Tickets cost $45–75 and the journey takes 6h. Flixbus USA also services this route twice daily.
- Website
- southwest.com
Flights from Louisville International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $55–390
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $50–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Louisville Bus Station to Chicago Bus Station
- Ave. Duration
- 6h
- Frequency
- 4 times a day
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Louisville Bus Station to Indianapolis Union Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a day
- Estimated price
- $17–29
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Louisville to Illinois is 296 miles. It takes approximately 5h 3m to drive from Louisville to Illinois.
Book your Louisville to Illinois bus tickets online with Omio and FlixBus.
There are 1285+ hotels available in Illinois.