There are 10 ways to get from Louisville to Iowa City by bus (Greyhound, Flixbus), car, plane, bus, bus (Flixbus, Greyhound), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Louisville Bus Station to Chicago Bus Stationbus Greyhound US0100
- Take the bus from Chicago Bus Station to Iowa Citybus Greyhound US0123S / ...
11h 15m$80–134Drive 470.9 mi
- Drive from Louisville to Iowa Citycar 470.9 mi
7h 59m$86–125Fly Louisville International Airport to The Eastern Iowa Airport, bus
- Fly from Louisville International Airport (SDF) to The Eastern Iowa Airport (CID)plane SDF - CID
- Take the bus from GTC Bay 9 to Court St Transportation Centerbus
8h 55mBus via Bloomington
- Take the bus from Louisville Bus Station to Bloomingtonbus
- Take the bus from Bloomington to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Iowa Citybus
13h 15m$84–136Bus, train
- Take the bus from Louisville Bus Station to Indianapolis Union Stationbus
- Take the train from Indianapolis to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Iowa Citybus
13h 19m$103–224Fly Louisville International Airport to Quad City International Airport, bus
- Fly from Louisville International Airport (SDF) to Quad City International Airport (MLI)plane SDF - MLI
- Take the bus from Moline Center Station to Iowa Citybus
9h 11m$87–479Drive to Blue Grass Airport, fly to The Eastern Iowa Airport, bus
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to The Eastern Iowa Airport (CID)plane LEX - CID
- Take the bus from GTC Bay 9 to Court St Transportation Centerbus
8h 58mFly Louisville International Airport to Chicago Midway International Airport, bus
- Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane SDF - MDW
- Take the bus from Chicago Bus Station to Iowa Citybus
8h 54m$99–468Fly Louisville International Airport to Chicago O'Hare International Airport, bus
- Fly from Louisville International Airport (SDF) to Chicago O'Hare International Airport (ORD)plane SDF - ORD
- Take the bus from Chicago Bus Station to Iowa Citybus
9h 23m$87–401Fly Louisville International Airport to Burlington Municipal Airport, drive
- Fly from Louisville International Airport (SDF) to Burlington Municipal Airport (BRL)plane SDF - BRL
- Drive from Burlington Municipal Airport (BRL) to Iowa Citycar
7h 18m$91–494
Louisville to Iowa City by bus
Comparing Your Travel Options
The cheapest way to get from Louisville to Iowa City is to bus which costs $80 - $140 and takes 11h 15m.
The fastest way to get from Louisville to Iowa City is to fly and drive which takes 7h 18m and costs $90 - $500.
No, there is no direct bus from Louisville station to Iowa City. However, there are services departing from Louisville Bus Station and arriving at Iowa City via Chicago Bus Station. The journey, including transfers, takes approximately 11h 15m.
The distance between Louisville and Iowa City is 524 miles. The road distance is 473.6 miles.
The best way to get from Louisville to Iowa City without a car is to bus which takes 11h 15m and costs $80 - $140.
It takes approximately 11h 15m to get from Louisville to Iowa City, including transfers.
Louisville to Iowa City bus services, operated by Greyhound USA, depart from Louisville Bus Station.
Louisville to Iowa City bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Iowa City is 1h behind Louisville. It is currently 7:21 PM in Louisville and 6:21 PM in Iowa City.
Yes, the driving distance between Louisville to Iowa City is 474 miles. It takes approximately 7h 59m to drive from Louisville to Iowa City.
What companies run services between Louisville, KY, USA and Iowa City, IA, USA?
You can take a bus from Louisville Bus Station to Iowa City via Chicago Bus Station in around 11h 15m.
- Website
- aa.com
Flights from Louisville International Airport to The Eastern Iowa Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $75–470
Flights from Louisville International Airport to The Eastern Iowa Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from Louisville International Airport to The Eastern Iowa Airport via Reagan Washington
- Ave. Duration
- 7h 16m
- When
- Every day
- Estimated price
- $140–700
Flights from Louisville International Airport to The Eastern Iowa Airport via Charlotte
- Ave. Duration
- 8h 19m
- When
- Every day
- Estimated price
- $120–650
Flights from Louisville International Airport to Quad City International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h
- When
- Every day
- Estimated price
- $75–460
Flights from Louisville International Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 5h 5m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–650
Flights from Louisville International Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 13m
- When
- Every day
- Estimated price
- $150–750
Flights from Blue Grass Airport to The Eastern Iowa Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $120–550
Flights from Blue Grass Airport to The Eastern Iowa Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 58m
- When
- Every day
- Estimated price
- $60–360
Flights from Blue Grass Airport to The Eastern Iowa Airport via Charlotte
- Ave. Duration
- 7h
- When
- Every day
- Estimated price
- $90–460
Flights from Louisville International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $45–330
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $45–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Louisville Bus Station to Chicago Bus Station
- Ave. Duration
- 6h
- Frequency
- 4 times a day
- Estimated price
- $45–75
- Website
- Greyhound
Bus from Chicago Bus Station to Iowa City
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Chicago Bus Station to Iowa City
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Louisville Bus Station to Indianapolis Union Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a day
- Estimated price
- $18–29
- Website
- Greyhound
Bus from Chicago Bus Station to Iowa City
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Moline Center Station to Iowa City
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $9–15
- Website
- Greyhound
Bus from Chicago Bus Station to Iowa City
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Chicago Bus Station to Iowa City
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
Booking & Getting There
Book your Louisville to Iowa City bus tickets online with Omio and FlixBus.
There are 50+ hotels available in Iowa City.





