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How to get fromLouisville to Irvineby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 7 ways to get from Louisville to Irvine by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to John Wayne Airport Orange County

    best
    1. Fly from Louisville International Airport (SDF) to John Wayne Airport Orange County (SNA)plane plane SDF - SNA
    7h 38m
    $212–903

  2. Fly Louisville International Airport to Los Angeles International Airport, train

    cheapest
    1. Fly from Louisville International Airport (SDF) to Los Angeles International Airport (LAX)plane plane SDF - LAX
    2. Take the train from L.A. Union Station to Tustintrain train
    10h 42m
    $137–578

  3. Bus

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles Union Station to Anaheim Regional Transportation Intermodal Centerbus bus
    2d 3h
    $403–679

  4. Bus, train via Chicago (Amtrak)

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus Nashville
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d 3h
    $1,256–1,967

  5. Drive  2,072 mi

    1. Drive from Louisville to Irvinecar car 2,072 mi
    32h 47m
    $379–547

  6. Drive to Covington, fly to Los Angeles International Airport, train

    1. Drive from Louisville to Covington (CVG)car car
    2. Fly from Covington (CVG) to Los Angeles International Airport (LAX)plane plane CVG - LAX
    3. Take the train from L.A. Union Station to Tustintrain train
    9h 18m
    $232–700

  7. Bus, train

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Pomona Amtraktrain train
    4. Take the bus from Ring-Brea Mall to Campus-University Centerbus bus 59
    2d 21h
    $1,370–2,277

Louisville to Irvine by bus

Calendar7Weekly Buses
Duration2d 3hAverage Duration
Ticket$403Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Irvine.ExpandLaunch map view
  • Distance: 1,820.7 mi
  • Duration: 7h 38m

What companies run services between Louisville, KY, USA and Irvine, CA, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Louisville International Airport (SDF) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a bus from Louisville, KY to Main-Harvard via Evansville Bus Station, St Louis Bus Station, Los Angeles Union Station, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 2d 3h.

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