There are 3 ways to get from Louisville to Isle of Palms by plane, bus (Amtrak, Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Louisville International Airport (SDF) to Charleston International Airport (CHS)plane SDF - CHS
3h 33m$432–513Drive 588.5 mi
cheapest- Drive from Louisville to Isle of Palmscar 588.5 mi
11h 28m$108–156Bus
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Charleston Bus Stationbus
21h 14m$193–331
Louisville International Airport (SDF) to Charleston International Airport (CHS) flights
Questions & Answers
The cheapest way to get from Louisville to Isle of Palms is to drive which costs $100 - $160 and takes 11h 28m.
The fastest way to get from Louisville to Isle of Palms is to fly which takes 3h 33m and costs $430 - $550.
No, there is no direct bus from Louisville to Isle of Palms station. However, there are services departing from Louisville, KY and arriving at Charleston Bus Station via Nashville Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 21h 14m.
The distance between Louisville and Isle of Palms is 517 miles. The road distance is 591.9 miles.
The best way to get from Louisville to Isle of Palms without a car is to bus which takes 21h 14m and costs $190 - $340.
It takes approximately 3h 33m to get from Louisville to Isle of Palms, including transfers.
Louisville to Isle of Palms bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
The best way to get from Louisville to Isle of Palms is to fly which takes 3h 33m and costs $430 - $550. Alternatively, you can bus, which costs $190 - $340 and takes 21h 14m.
Louisville to Isle of Palms bus services, operated by Amtrak Thruway, arrive at Nashville station.
Yes, the driving distance between Louisville to Isle of Palms is 592 miles. It takes approximately 11h 28m to drive from Louisville to Isle of Palms.
What companies run services between Louisville, KY, USA and Isle of Palms, SC, USA?
Breeze Airways, Southwest Airlines, and two other airlines fly from Louisville International Airport (SDF) to Charleston International Airport (CHS) 5 times a day. Alternatively, you can take a bus from Louisville, KY to Isle of Palms via Nashville Bus Station, Atlanta Bus Station, and Charleston Bus Station in around 21h 14m.
- Website
- aa.com
Flights from Louisville International Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $80–470
- Website
- delta.com
Flights from Louisville International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $85–490
- Website
- flybreeze.com
Flights from Louisville International Airport to Charleston International Airport
- Ave. Duration
- 1h 38m
- When
- Monday and Friday
- Estimated price
- $340–400
- Website
- southwest.com
Flights from Louisville International Airport to Charleston International Airport via Nashville
- Ave. Duration
- 3h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $85–490
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Atlanta Bus Station to Charleston Bus Station
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- $65–140
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 1165+ hotels available in Isle of Palms.