There are 7 ways to get from Louisville to Key Largo by plane, shuttle, bus (Amtrak, Greyhound, Flixbus), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Miami International Airport, shuttle
best- Fly from Louisville International Airport (SDF) to Miami International Airport (MIA)plane SDF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 15m$212–733Bus
cheapest- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
25h 20m$166–322Drive 1,076.3 mi
- Drive from Louisville to Key Largocar 1,076.3 mi
19h 50m$197–284Fly Louisville International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Louisville International Airport (SDF) to Fort Lauderdale–Hollywood International Airport (FLL)plane SDF - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 43m$422–953Drive to Blue Grass Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Fort Lauderdale–Hollywood International Airport (FLL)plane LEX - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
6h 31m$223–629Bus to Covington, fly to Miami International Airport, shuttle
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus
- Fly from Covington (CVG) to Miami International Airport (MIA)plane CVG - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
8h 35m$292–975Bus via Pembroke Pines
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Hollywood Sheridan Trirail Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
29h 46m$169–318
Louisville to Key Largo by bus
Questions & Answers
The cheapest way to get from Louisville to Key Largo is to bus which costs $160 - $330 and takes 25h 20m.
The fastest way to get from Louisville to Key Largo is to fly and shuttle which takes 6h 15m and costs $210 - $750.
No, there is no direct bus from Louisville to Key Largo. However, there are services departing from Louisville, KY and arriving at Key Largo Bus Stop via Nashville Bus Station, Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 25h 20m.
The distance between Louisville and Key Largo is 983 miles. The road distance is 1082.6 miles.
The best way to get from Louisville to Key Largo without a car is to bus which takes 25h 20m and costs $160 - $330.
It takes approximately 6h 15m to get from Louisville to Key Largo, including transfers.
Louisville to Key Largo bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Key Largo bus services, operated by Amtrak Thruway, arrive at Nashville station.
Yes, the driving distance between Louisville to Key Largo is 1083 miles. It takes approximately 19h 50m to drive from Louisville to Key Largo.
Book your Louisville to Key Largo bus tickets online with Omio.
What companies run services between Louisville, KY, USA and Key Largo, FL, USA?
You can take a bus from Louisville, KY to Key Largo Bus Stop via Nashville Bus Station, Atlanta Bus Station, and Miami Airport Station in around 25h 20m.
- Website
- southwest.com
Flights from Louisville International Airport to Miami International Airport via Orlando
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $110–600
Flights from Louisville International Airport to Miami International Airport via Nashville
- Ave. Duration
- 5h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–600
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport via Orlando
- Ave. Duration
- 4h 20m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport via Nashville
- Ave. Duration
- 4h 32m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $120–600
Flights from Louisville International Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 5h 25m
- When
- Tuesday and Wednesday
- Estimated price
- $110–600
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $120–150
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a day
- Estimated price
- $100–130
- Website
- Keys Shuttle
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More Questions & Answers
There are 337+ hotels available in Key Largo.

