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How to get fromLouisville to Lake Cityby plane, bus, bus (Greyhound, Flixbus), car, or bus (Greyhound)

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There are 11 ways to get from Louisville to Lake City by plane, bus, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Jacksonville, bus

    best
    1. Fly from Louisville International Airport (SDF) to Jacksonville (JAX)plane plane SDF - JAX
    2. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    8h 33m
    $292–624

  2. Fly Louisville International Airport to Valdosta, bus

    cheapest
    1. Fly from Louisville International Airport (SDF) to Valdosta (VLD)plane plane SDF - VLD
    2. Take the bus from Valdosta to Gainesville Bus Stopbus bus
    3. Take the bus from Gainesville Bus Stop to Lake City Bus Stationbus bus
    10h 16m
    $111–482

  3. Bus

    1. Take the bus from Louisville Bus Station to Atlanta Bus Stationbus bus Greyhound US0135 / ...
    2. Take the bus from Atlanta Bus Station to Lake City Bus Stationbus bus FlixBus 2451
    14h 55m

  4. Drive 661.5 mi

    1. Drive from Louisville to Lake Citycar car 661.5 mi
    12h 11m
    $121–175

  5. Fly Louisville International Airport to Gainesville Regional Airport, bus

    1. Fly from Louisville International Airport (SDF) to Gainesville Regional Airport (GNV)plane plane SDF - GNV
    2. Take the bus from Gainesville to Lake City Bus Stationbus bus
    8h 27m

  6. Fly Louisville International Airport to Orlando, bus

    1. Fly from Louisville International Airport (SDF) to Orlando (MCO)plane plane SDF - MCO
    2. Take the bus from Orlando Bus Station to Lake City Bus Stationbus bus
    9h 29m
    $300–857

  7. Bus to Nashville, fly to Jacksonville, bus

    1. Take the bus from Louisville Bus Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Jacksonville (JAX)plane plane BNA - JAX
    3. Take the bus from Jacksonville to Lake City Bus Stationbus bus
    9h 37m
    $114–504

  8. Fly Louisville International Airport to Orlando Sanford, drive

    1. Fly from Louisville International Airport (SDF) to Orlando Sanford (SFB)plane plane SDF - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Lake Citycar car
    6h 29m
    $120–518

  9. Fly Louisville International Airport to Hartsfield-Jackson Atlanta International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane SDF - ATL
    2. Take the bus from Atlanta Bus Station to Lake City Bus Stationbus bus
    9h 35m

  10. Fly Louisville International Airport to Tampa, bus

    1. Fly from Louisville International Airport (SDF) to Tampa (TPA)plane plane SDF - TPA
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus
    3. Take the bus from Gainesville to Lake City Bus Stationbus bus
    10h 12m

  11. Bus via Montgomery

    1. Take the bus from Louisville Bus Station to Montgomery Intermodal Centerbus bus
    2. Take the bus from Montgomery Intermodal Center to Tallahasseebus bus
    3. Take the bus from Tallahassee to Lake City Bus Stationbus bus
    18h 50m
    $122–234

Louisville International Airport (SDF) to Jacksonville (JAX) flights

Calendar78Weekly Planes
Duration5h 14mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Lake City.ExpandLaunch map view
  • Distance: 664.2 mi
  • Duration: 8h 33m

What companies run services between Louisville, KY, USA and Lake City, FL, USA?

You can take a bus from Louisville Bus Station to Lake City Bus Station via Atlanta Bus Station in around 14h 55m.

Airlines
Bus operators

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