There are 10 ways to get from Louisville to Lancaster by plane, train, bus (Flixbus), car, subway, bus (Greyhound), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Philadelphia International Airport, train
best- Fly from Louisville International Airport (SDF) to Philadelphia International Airport (PHL)plane SDF - PHL
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
8h 40m$142–666Bus via Columbus
cheapest- Take the bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus Louisville
- Take the bus from Wilson & Ferrell Shell Station - Columbus to Harrisburg Bus Stationbus Greyhound US0421
18h 7m$80–180Bus
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus Louisville
- Take the bus from Cincinnati to Harrisburg Bus Stationbus FlixBus N2642
17h 44m$96–198Drive 600.8 mi
- Drive from Louisville to Lancastercar 600.8 mi
10h 25m$110–159Drive to Blue Grass Airport, fly to Philadelphia International Airport, train
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Philadelphia International Airport (PHL)plane LEX - PHL
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
8h 21m$173–832Fly Louisville International Airport to Baltimore-Washington International Airport, train
- Fly from Louisville International Airport (SDF) to Baltimore-Washington International Airport (BWI)plane SDF - BWI
- Take the train from BWI Thurgood Marshall to 30th Street Stationtrain
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
9h 49m$143–1,265Fly Louisville International Airport to Ronald Reagan Washington National Airport, train
- Fly from Louisville International Airport (SDF) to Ronald Reagan Washington National Airport (DCA)plane SDF - DCA
- Take the train from Washington Union Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
10h 7m$183–810Fly Louisville International Airport to Newark Liberty International Airport, train
- Fly from Louisville International Airport (SDF) to Newark Liberty International Airport (EWR)plane SDF - EWR
- Take the train from Newark Liberty International Airport to 30th Street Stationtrain
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
10h 26m$124–488Fly Louisville International Airport to Washington Dulles International Airport, subway, train
- Fly from Louisville International Airport (SDF) to Washington Dulles International Airport (IAD)plane SDF - IAD
- Take the subway from Washington Dulles International Airport, Silver Line Center Platform to Farragut West, Blue/Orange/Silver Line Track 1 Platformsubway
- Take the train from Washington Union Station to 30th Street Stationtrain
- Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain
10h 34m$143–569Bus, train
- Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus
- Take the bus from Columbus to Pittsburgh Intermodal Stationbus
- Take the train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Stationtrain
18h 24m$128–294
Louisville to Lancaster by bus and train
Questions & Answers
The cheapest way to get from Louisville to Lancaster is to bus via Columbus which costs $80 - $180 and takes 18h 7m.
The fastest way to get from Louisville to Lancaster is to drive and fly and train which takes 8h 21m and costs $170 - $850.
No, there is no direct bus from Louisville station to Lancaster. However, there are services departing from Louisville, KY Bus Station and arriving at W. Chestnut & Water St. via 7Th St & Plum St, Government Square Area H, Cincinnati and AMTRAK ETown. The journey, including transfers, takes approximately 17h 44m.
The distance between Louisville and Lancaster is 701 miles. The road distance is 604.3 miles.
The best way to get from Louisville to Lancaster without a car is to bus which takes 17h 44m and costs $95 - $200.
It takes approximately 8h 40m to get from Louisville to Lancaster, including transfers.
Louisville to Lancaster bus services, operated by Barons Bus, depart from Louisville, KY Bus Station.
Louisville to Lancaster bus services, operated by Barons Bus, arrive at Cincinnati - Downtown station.
Yes, the driving distance between Louisville to Lancaster is 604 miles. It takes approximately 10h 25m to drive from Louisville to Lancaster.
Book your Louisville to Lancaster bus tickets online with Omio.
What companies run services between Louisville, KY, USA and Lancaster, PA, USA?
You can take a bus from Louisville, KY Bus Station to W. Chestnut & Water St. via Cincinnati - Downtown, 7Th St & Plum St, Government Square Area A, Government Square Area H, Martin Luther King Dr & Jefferson Ave WB, Cincinnati, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 17h 44m.
- Website
- southwest.com
Flights from Louisville International Airport to Philadelphia International Airport via Chicago Midway
- Ave. Duration
- 4h 22m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $150–750
Flights from Louisville International Airport to Philadelphia International Airport via Nashville
- Ave. Duration
- 4h 15m
- When
- Saturday
- Estimated price
- $140–700
Flights from Louisville International Airport to Baltimore-Washington International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–550
Flights from Louisville International Airport to Baltimore-Washington International Airport via Nashville
- Ave. Duration
- 4h
- When
- Monday to Wednesday
- Estimated price
- $110–600
Flights from Louisville International Airport to Baltimore-Washington International Airport via Chicago Midway
- Ave. Duration
- 4h
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–650
Flights from Louisville International Airport to Ronald Reagan Washington National Airport via Nashville
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Louisville International Airport to Ronald Reagan Washington National Airport via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $160–800
- Website
- aa.com
Flights from Louisville International Airport to Philadelphia International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $110–600
Flights from Louisville International Airport to Philadelphia International Airport via Ronald Reagan Washington National Airport
- Ave. Duration
- 4h 10m
- When
- Monday to Saturday
- Estimated price
- $110–600
Flights from Blue Grass Airport to Philadelphia International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $130–750
Flights from Blue Grass Airport to Philadelphia International Airport via Charlotte
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $160–850
Flights from Louisville International Airport to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $110–650
Flights from Louisville International Airport to Ronald Reagan Washington National Airport via Charlotte
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $130–700
Flights from Louisville International Airport to Washington Dulles International Airport via Charlotte
- Ave. Duration
- 4h 3m
- When
- Sunday
- Estimated price
- $85–470
- Website
- united.com
Flights from Louisville International Airport to Philadelphia International Airport via Washington Dulles International Airport
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $110–600
Flights from Louisville International Airport to Newark Liberty International Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- $70–370
Flights from Louisville International Airport to Newark Liberty International Airport via Washington Dulles International Airport
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $70–380
Flights from Louisville International Airport to Washington Dulles International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $70–410
- Website
- delta.com
Flights from Louisville International Airport to Philadelphia International Airport via Detroit
- Ave. Duration
- 4h 51m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Blue Grass Airport to Philadelphia International Airport via Detroit
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $160–850
Flights from Blue Grass Airport to Philadelphia International Airport via Atlanta
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $190–950
Flights from Louisville International Airport to Baltimore-Washington International Airport via Detroit
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $110–600
Flights from Louisville International Airport to Ronald Reagan Washington National Airport via Detroit
- Ave. Duration
- 4h 11m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Louisville International Airport to Newark Liberty International Airport via Detroit
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $80–400
Flights from Louisville International Airport to Washington Dulles International Airport via Detroit
- Ave. Duration
- 3h 53m
- When
- Saturday
- Estimated price
- $90–470
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from BWI Thurgood Marshall to 30th Street Station
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $30–70
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from Washington Union Station to 30th Street Station
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $40–90
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from Newark Liberty International Airport to 30th Street Station
- Ave. Duration
- 1h 3m
- Frequency
- Every 2 hours
- Estimated price
- $25–55
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from Washington Union Station to 30th Street Station
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $40–90
- Website
- Amtrak
Train from 30th Street Station to Elizabethtown Amtrak Station
- Ave. Duration
- 1h 32m
- Frequency
- Every 2 hours
- Estimated price
- $27–60
- Website
- Amtrak
Train from Pittsburgh Amtrak Station to Elizabethtown Amtrak Station
- Ave. Duration
- 5h 52m
- Frequency
- Once daily
- Estimated price
- $80–180
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from BWI Thurgood Marshall to 30th Street Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from Washington Union Station to 30th Street Station
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
Train from Washington Union Station to 30th Street Station
- Ave. Duration
- 1h 42m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
Subway from Washington Dulles International Airport, Silver Line Center Platform to Farragut West, Blue/Orange/Silver Line Track 1 Platform
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- Washington Metropolitan Area Transit Authority
- standard fare after 9:30 p.m
- $2–3
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $9–45
- Website
- Barons Bus
Bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbus
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- Barons Bus
Bus from Louisville, KY Bus Station to Columbus - Downtown - Mound St
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- $21–60
- Website
- Barons Bus
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Cincinnati to Harrisburg Bus Station
- Ave. Duration
- 10h 35m
- Frequency
- Once daily
- Estimated price
- $80–140
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Wilson & Ferrell Shell Station - Columbus to Harrisburg Bus Station
- Ave. Duration
- 9h 55m
- Frequency
- Every 4 hours
- Estimated price
- $55–110
- Website
- Greyhound
Bus from Columbus to Pittsburgh Intermodal Station
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $27–55
- Website
- Greyhound
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