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How to get fromLouisville to Lewisburgby plane, bus, bus (Flixbus), car, train, or bus (Greyhound)

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There are 6 ways to get from Louisville to Lewisburg by plane, bus, bus (Flixbus), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport, bus

    best
    1. Fly from Louisville International Airport (SDF) to Harrisburg International Airport (MDT)plane plane SDF - MDT
    2. Take the bus from Harrisburg, Pa to Lewisburgbus bus
    8h 33m
    $96–495

  2. Bus via Columbus

    cheapest
    1. Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus bus
    2. Take the bus from Columbus to Harrisburg Bus Stationbus bus
    3. Take the bus from Harrisburg, Pa to Lewisburgbus bus 29
    17h 35m
    $94–209

  3. Bus

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Take the bus from Cincinnati to Harrisburg Bus Stationbus bus
    3. Take the bus from Harrisburg, Pa to Lewisburgbus bus 29
    17h 5m
    $105–219

  4. Drive 575.2 mi

    1. Drive from Louisville to Lewisburgcar car 575.2 mi
    10h 34m
    $105–152

  5. Fly to Newark Liberty International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Newark Liberty International Airport (EWR)plane plane SDF - EWR
    2. Take the bus from Newark to Allentownbus bus
    3. Take the bus from Allentown to Lewisburgbus bus
    9h 35m

  6. Fly to Philadelphia International Airport, train, bus

    1. Fly from Louisville International Airport (SDF) to Philadelphia International Airport (PHL)plane plane SDF - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    3. Take the bus from Harrisburg, Pa to Lewisburgbus bus
    9h 37m
    $153–716

Louisville to Lewisburg by bus and foot

Calendar5Weekly Services
Duration17h 5mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Lewisburg.ExpandLaunch map view
  • Distance: 584.5 mi
  • Duration: 8h 33m

What companies run services between Louisville, KY, USA and Lewisburg, PA, USA?

You can take a bus from Louisville, KY Bus Station to Lewisburg via Cincinnati - Downtown, 9Th St & Race St, Northside Transit Center - Shelter B, Vine St & Martin Luther King Dr, Cincinnati, and Harrisburg, Pa in around 17h 5m.

Airlines
Train operators
Bus operators

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