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How to get fromLouisville to Manchesterby plane, bus (Greyhound), bus, train, car, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Louisville to Manchester by plane, bus (Greyhound), bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Manchester Airport

    best
    1. Fly from Louisville International Airport (SDF) to Manchester Airport (MHT)plane plane SDF - MHT
    7h 38m
    $103–555

  2. Bus via Brook Park

    1. Take the bus from Louisville, KY Bus Station to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Bostonbus bus
    4. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    25h 15m
    $146–304

  3. Bus, train via Cleveland

    1. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus bus
    2. Take the train from Cleveland Amtrak to Bostontrain train
    3. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    25h 20m
    $256–549

  4. Drive 953 mi

    1. Drive from Louisville to Manchestercar car 953 mi
    17h 33m
    $174–252

  5. Fly Louisville International Airport to Boston Logan Airport, bus

    1. Fly from Louisville International Airport (SDF) to Boston Logan Airport (BOS)plane plane SDF - BOS
    2. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    6h 34m
    $106–504

  6. Bus to Covington, fly to Boston Logan Airport, bus

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Boston Logan Airport (BOS)plane plane CVG - BOS
    3. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    8h 34m
    $421–1,066

  7. Bus

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Take the bus from Cincinnati to New York Midtownbus bus
    3. Take the bus from New York Midtown to Bostonbus bus
    4. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    26h 59m
    $170–325

  8. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    4. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    32h 6m
    $406–870

Louisville to Manchester by bus

Calendar7Weekly Buses
Duration25h 15mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Manchester.ExpandLaunch map view
  • Distance: 829.7 mi
  • Duration: 7h 38m

What companies run services between Louisville, KY, USA and Manchester, NH, USA?

Southwest Airlines, United Airlines, and American Airlines fly from Louisville International Airport (SDF) to Manchester Airport (MHT) every 3 hours. Alternatively, you can take a bus from Louisville, KY Bus Station to Manchester(Veterans Memorial Park) via Robert K Pfaff Transit Center - Akron, Cleveland Bus Station, and Boston in around 25h 15m.

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