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How to get fromLouisville to Manhattanby plane, bus (Greyhound), bus, train, or car

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There are 7 ways to get from Louisville to Manhattan by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Manhattan Regional Airport

    best
    1. Fly from Louisville International Airport (SDF) to Manhattan Regional Airport (MHK)plane plane SDF - MHK
    6h 36m
    $127–533

  2. Drive 624.4 mi

    cheapest
    1. Drive from Louisville to Manhattancar car 624.4 mi
    10h 23m
    $114–165

  3. Bus

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Manhattan KSbus bus
    15h 55m
    $123–221

  4. Bus, train, drive (Amtrak)

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Topeka Stationtrain train
    4. Drive from Topeka Station to Manhattancar car
    19h 54m
    $253–520

  5. Drive to Blue Grass Airport, fly to Manhattan Regional Airport

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Manhattan Regional Airport (MHK)plane plane LEX - MHK
    7h 19m
    $163–709

  6. Bus to Covington, fly to Manhattan Regional Airport

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Manhattan Regional Airport (MHK)plane plane CVG - MHK
    9h 2m
    $142–635

  7. Fly Louisville International Airport to Salina Municipal Airport, bus

    1. Fly from Louisville International Airport (SDF) to Salina Municipal Airport (SLN)plane plane SDF - SLN
    2. Take the bus from Salina to Manhattan KSbus bus
    10h 3m
    $124–588

Louisville to Manhattan by bus

Calendar7Weekly Buses
Duration15h 55mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Manhattan.ExpandLaunch map view
  • Distance: 606.8 mi
  • Duration: 6h 36m

What companies run services between Louisville, KY, USA and Manhattan, KS, USA?

American Airlines and United Airlines fly from Louisville International Airport (SDF) to Manhattan Regional Airport (MHK) every 4 hours. Alternatively, you can take a bus from Louisville, KY to Manhattan KS via Evansville Bus Station and St Louis Bus Station in around 15h 55m.

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