There are 10 ways to get from Louisville to Mebane by plane, bus, bus (Greyhound, Flixbus), train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Piedmont Triad International Airport, bus
best- Fly from Louisville International Airport (SDF) to Piedmont Triad International Airport (GSO)plane SDF - GSO
- Take the bus from Coble Transportation Center to Mebane Cone Health Park & Ridebus
9h$164–929Drive 475.8 mi
cheapest- Drive from Louisville to Mebanecar 475.8 mi
9h 9m$87–126Bus via Atlanta
- Take the bus from Louisville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Durhambus
- Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus Odx
18h 31m$120–201Bus, train
- Take the bus from Louisville Bus Station to Indianapolis Union Stationbus
- Take the train from Indianapolis to Charlottesvilletrain
- Take the train from Charlottesville to Greensborotrain
- Take the bus from Greensboro Depot to Mebane Cone Health Park & Ridebus 4
25h 57m$219–510Bus to Covington, fly to Raleigh-Durham International Airport, bus
- Take the bus from Louisville to Cincinnatibus
- Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane CVG - RDU
- Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus
8h 24m$111–654Fly Louisville International Airport to Raleigh-Durham International Airport, bus
- Fly from Louisville International Airport (SDF) to Raleigh-Durham International Airport (RDU)plane SDF - RDU
- Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus
6h 13m$201–1,312Fly Louisville International Airport to Charlotte Douglas International Airport, train, bus
- Fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT)plane SDF - CLT
- Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
- Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus
9h 32m$134–702Bus to Indianapolis, fly to Raleigh-Durham International Airport, bus
- Take the bus from Louisville Bus Station to Indianapolis Union Stationbus
- Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane IND - RDU
- Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus
9h 17m$202–437Drive to Blue Grass Airport, fly to Charlotte Douglas International Airport, train, bus
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Charlotte Douglas International Airport (CLT)plane LEX - CLT
- Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain
- Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus
9h 26m$120–568Bus
- Take the bus from Louisville to Columbusbus
- Take the bus from Columbus to Winston Salem(Trans Center)bus
- Take the bus from Coble Transportation Center to Mebane Cone Health Park & Ridebus 4
19h 6m$108–172
Louisville to Mebane by bus
Comparing Your Travel Options
The cheapest way to get from Louisville to Mebane is to drive which costs $85 - $130 and takes 9h 9m.
The fastest way to get from Louisville to Mebane is to fly and bus which takes 6h 13m and costs $200 - $1,400.
No, there is no direct bus from Louisville station to Mebane. However, there are services departing from Louisville Bus Station and arriving at E Washington St at S 5th St via Atlanta Bus Station and Willard St at Durham Station. The journey, including transfers, takes approximately 18h 31m.
The distance between Louisville and Mebane is 411 miles. The road distance is 478.6 miles.
The best way to get from Louisville to Mebane without a car is to bus via Atlanta which takes 18h 31m and costs $120 - $210.
It takes approximately 9h to get from Louisville to Mebane, including transfers.
Louisville to Mebane bus services, operated by Greyhound USA, depart from Louisville Bus Station.
Louisville to Mebane bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Louisville to Mebane is 479 miles. It takes approximately 9h 9m to drive from Louisville to Mebane.
There are 63+ hotels available in Mebane.
What companies run services between Louisville, KY, USA and Mebane, NC, USA?
You can take a bus from Louisville Bus Station to E Washington St at S 5th St via Atlanta Bus Station and Willard St at Durham Station in around 18h 31m.
- Website
- aa.com
Flights from Louisville International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $140–900
Flights from Louisville International Airport to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $180–1,100
Flights from Louisville International Airport to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Louisville International Airport to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Covington to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $100–600
Flights from Louisville International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $90–600
Flights from Indianapolis to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $90–550
Flights from Blue Grass Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $65–450
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Charlottesville
- Ave. Duration
- 15h 20m
- Frequency
- 3 times a week
- Estimated price
- $150–360
- Website
- Amtrak
Train from Charlottesville to Greensboro
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- $40–100
- Website
- Amtrak
Train from Charlotte Amtrak Station to Durham Amtrak Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $35–90
- Website
- Amtrak
Train from Charlotte Amtrak Station to Durham Amtrak Station
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a day
- Estimated price
- $35–90
- Website
- Amtrak
- Phone
- +1 336-662-0002
- Website
- partnc.org
Bus from Coble Transportation Center to Mebane Cone Health Park & Ride
- Ave. Duration
- 1h 27m
- Frequency
- Twice daily
- Estimated price
- $2–3
- Website
- http://www.partnc.org
- Schedules at
- https://www.partnc.org/27/Routes-Schedules
Bus from Greensboro Depot to Mebane Cone Health Park & Ride
- Ave. Duration
- 1h 2m
- Frequency
- 4 times a day
- Estimated price
- $1–3
- Website
- http://www.partnc.org
- Schedules at
- https://www.partnc.org/27/Routes-Schedules
Bus from Coble Transportation Center to Mebane Cone Health Park & Ride
- Ave. Duration
- 1h 27m
- Frequency
- Twice daily
- Estimated price
- $2–3
- Website
- http://www.partnc.org
- Schedules at
- https://www.partnc.org/27/Routes-Schedules
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