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How to get fromLouisville to Mebaneby plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Amtrak, Greyhound)

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There are 8 ways to get from Louisville to Mebane by plane, bus, bus (Amtrak, Greyhound, Flixbus), train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Raleigh-Durham International Airport, bus

    best
    1. Fly from Louisville International Airport (SDF) to Raleigh-Durham International Airport (RDU)plane plane SDF - RDU
    2. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus
    6h 13m
    $106–612

  2. Drive  475.8 mi

    cheapest
    1. Drive from Louisville to Mebanecar car 475.8 mi
    9h 9m
    $87–126

  3. Bus via Atlanta

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Downtown to Durhambus bus
    4. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus Odx
    18h 20m
    $134–207

  4. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Charlottesvilletrain train
    3. Take the train from Charlottesville to Greensborotrain train
    4. Take the bus from Greensboro Depot to Mebane Cone Health Park & Ridebus bus 4
    26h 22m
    $449–750

  5. Drive to Covington, fly to Raleigh-Durham International Airport, bus

    1. Drive from Louisville to Covington (CVG)car car
    2. Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane plane CVG - RDU
    3. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus
    6h 26m
    $146–784

  6. Fly Louisville International Airport to Piedmont Triad International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Piedmont Triad International Airport (GSO)plane plane SDF - GSO
    2. Take the bus from Coble Transportation Center to Mebane Cone Health Park & Ridebus bus
    8h 34m
    $89–449

  7. Bus

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Durhambus bus
    4. Take the bus from Willard St at Durham Station to E Washington St at S 5th Stbus bus Odx
    18h 26m
    $131–224

  8. Bus #2

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Columbusbus bus
    3. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    4. Take the bus from Coble Transportation Center to Mebane Cone Health Park & Ridebus bus 4
    23h 16m
    $137–223

Louisville to Mebane by bus and subway

Calendar4Weekly Services
Duration18h 20mAverage Duration
Ticket$134Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Mebane.ExpandLaunch map view
  • Distance: 466 mi
  • Duration: 6h 13m

What companies run services between Louisville, KY, USA and Mebane, NC, USA?

You can take a bus from Louisville, KY to E Washington St at S 5th St via Nashville Bus Station, Atlanta Bus Station, Garnett Station, Civic Center Station, Atlanta Downtown, and Willard St at Durham Station in around 18h 20m.

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Bus operators

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