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How to get fromLouisville to Milwaukeeby bus, train, car, plane, bus (Greyhound, Flixbus), or bus (Amtrak)

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There are 8 ways to get from Louisville to Milwaukee by bus, train, car, plane, bus (Greyhound, Flixbus), or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Louisville Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    8h 38m
    $66–142

  2. Bus

    cheapest
    1. Take the bus from Louisville Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150
    8h 40m
    $57–120

  3. Bus, train via Indianapolis

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    10h 24m
    $95–214

  4. Drive  382.3 mi

    1. Drive from Louisville to Milwaukeecar car 382.3 mi
    6h 45m
    $70–101

  5. Fly to General Mitchell International Airport

    1. Fly from Louisville International Airport (SDF) to General Mitchell International Airport (MKE)plane plane SDF - MKE
    5h 14m
    $95–606

  6. Bus via Lafayette

    1. Take the bus from Louisville, KY to Lafayette Amtrak Stationbus bus
    2. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    3. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus
    9h 39m
    $127–163

  7. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Chicago O'Hare International Airport (ORD)plane plane SDF - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    5h 36m
    $66–373

  8. Fly to Chicago Midway International Airport, train

    1. Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane plane SDF - MDW
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    6h 3m
    $84–451

Louisville to Milwaukee by bus, foot, and train

Calendar40Weekly Services
Duration8h 38mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Milwaukee.ExpandLaunch map view
  • Distance: 383.6 mi
  • Duration: 8h 38m

What companies run services between Louisville, KY, USA and Milwaukee, WI, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a bus from Louisville Bus Station to Milwaukee Intermodal Station via Chicago Bus Station in around 8h 40m.

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