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How to get fromLouisville to Mississippiby plane, bus (Amtrak, Greyhound, Flixbus), car, or bus (Greyhound)

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There are 6 ways to get from Louisville to Mississippi by plane, bus (Amtrak, Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Memphis

    best
    1. Fly from Louisville International Airport (SDF) to Memphis (MEM)plane plane SDF - MEM
    4h 39m
    $144–830

  2. Bus via Nashville

    cheapest
    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Jacksonbus bus
    12h 10m
    $98–156

  3. Drive  562.3 mi

    1. Drive from Louisville to Jacksoncar car 562.3 mi
    10h 12m
    $103–149

  4. Fly to Gulfport-Biloxi Regional Airport

    1. Fly from Louisville International Airport (SDF) to Gulfport-Biloxi Regional Airport (GPT)plane plane SDF - GPT
    5h 22m
    $113–567

  5. Fly to Jackson/Vicksburg

    1. Fly from Louisville International Airport (SDF) to Jackson/Vicksburg (JAN)plane plane SDF - JAN
    5h 33m
    $127–533

  6. Bus

    1. Take the bus from La Tropicana - Louisville, KY to El Mezcal Grocery - Jackson, TNbus bus
    2. Take the bus from Jackson to Memphis - Summer Avebus bus Nyc
    3. Take the bus from Memphis Bus Station to Jacksonbus bus
    17h 11m
    $133–189

Louisville to Mississippi by bus

Calendar7Weekly Buses
Duration12h 10mAverage Duration
Ticket$98Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Mississippi.ExpandLaunch map view
  • Distance: 333.5 mi
  • Duration: 4h 39m

What companies run services between Louisville, KY, USA and Mississippi, USA?

Southwest Airlines, Delta, and two other airlines fly from Louisville International Airport (SDF) to Memphis (MEM) hourly. Alternatively, you can take a bus from Louisville, KY to Jackson via Nashville Bus Station and Memphis Bus Station in around 12h 10m.

Airlines
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