There are 6 ways to get from Louisville to Missouri by plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Lambert–St. Louis International Airport
best- Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane SDF - STL
5h 36m$105–606Drive 505.6 mi
cheapest- Drive from Louisville to Kansas Citycar 505.6 mi
8h 26m$93–134Bus
- Take the bus from Louisville, KY to Evansville, INbus
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Kansas City Bus Stationbus
11h 40m$104–176Bus, train
- Take the bus from Louisville, KY to Evansville, INbus
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus
- Take the train from St. Louis to Kansas Citytrain
13h 32m$154–291Fly Louisville International Airport to Kansas City
- Fly from Louisville International Airport (SDF) to Kansas City (MCI)plane SDF - MCI
6h 48m$132–753Bus to Nashville, fly to Lambert–St. Louis International Airport
- Take the bus from Louisville, KY to Nashvillebus
- Fly from Nashville (BNA) to Lambert–St. Louis International Airport (STL)plane BNA - STL
6h 32m$118–521
Louisville to Missouri by bus
Questions & Answers
The cheapest way to get from Louisville to Missouri is to drive which costs $90 - $140 and takes 8h 26m.
The fastest way to get from Louisville to Missouri is to fly which takes 5h 36m and costs $100 - $650.
No, there is no direct bus from Louisville to Missouri station. However, there are services departing from Louisville, KY and arriving at Kansas City Bus Station via Evansville Bus Station and St Louis Bus Station. The journey, including transfers, takes approximately 11h 40m.
The distance between Louisville and Missouri is 275 miles. The road distance is 508.5 miles.
The best way to get from Louisville to Missouri without a car is to bus which takes 11h 40m and costs $100 - $180.
It takes approximately 5h 36m to get from Louisville to Missouri, including transfers.
Louisville to Missouri bus services, operated by Miller Transportation, depart from Louisville, KY station.
The best way to get from Louisville to Missouri is to fly which takes 5h 36m and costs $100 - $650. Alternatively, you can bus, which costs $100 - $180 and takes 11h 40m.
Louisville to Missouri bus services, operated by Miller Transportation, arrive at Evansville, IN station.
Missouri is 1h behind Louisville. It is currently 2:35 AM in Louisville and 1:35 AM in Missouri.
What companies run services between Louisville, KY, USA and Missouri, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Louisville, KY to Kansas City Bus Station via Evansville Bus Station and St Louis Bus Station in around 11h 40m.
- Website
- southwest.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 40m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $110–650
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 5h 46m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $100–600
Flights from Louisville International Airport to Kansas City via Nashville
- Ave. Duration
- 4h 5m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $130–750
Flights from Louisville International Airport to Kansas City via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–750
Flights from Louisville International Airport to Kansas City via Dallas
- Ave. Duration
- 5h 10m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $210–950
Flights from Nashville to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $75–500
- Website
- delta.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $140–750
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $140–700
Flights from Louisville International Airport to Kansas City via Detroit
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $170–850
Flights from Louisville International Airport to Kansas City via Atlanta
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $180–850
Flights from Louisville International Airport to Kansas City via Minneapolis
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $180–850
- Website
- united.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $110–650
Flights from Louisville International Airport to Kansas City via Chicago O'Hare
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $140–750
- Website
- aa.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $110–650
Flights from Louisville International Airport to Kansas City via Chicago O'Hare
- Ave. Duration
- 5h 52m
- When
- Saturday
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Kansas City
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $26–50
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
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More Questions & Answers
Yes, the driving distance between Louisville to Missouri is 509 miles. It takes approximately 8h 26m to drive from Louisville to Missouri.
There are 341+ hotels available in Missouri.










