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How to get fromLouisville to Mobileby plane, bus (Greyhound, Amtrak, Flixbus), car, bus, or bus (Greyhound)

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There are 7 ways to get from Louisville to Mobile by plane, bus (Greyhound, Amtrak, Flixbus), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Mobile Regional Airport

    best
    1. Fly from Louisville International Airport (SDF) to Mobile Regional Airport (MOB)plane plane SDF - MOB
    5h 44m
    $117–543

  2. Bus via Nashville

    cheapest
    1. Take the bus from Louisville Bus Station to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus bus
    13h 55m
    $92–158

  3. Drive  597.8 mi

    1. Drive from Louisville to Mobilecar car 597.8 mi
    10h 59m
    $110–158

  4. Drive to Blue Grass Airport, fly to Mobile Regional Airport

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Mobile Regional Airport (MOB)plane plane LEX - MOB
    5h 55m
    $108–439

  5. Fly Louisville International Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Louisville International Airport (SDF) to Destin–Fort Walton Beach Airport (VPS)plane plane SDF - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Mobilecar car
    5h 16m
    $101–511

  6. Fly Louisville International Airport to Gulfport-Biloxi Regional Airport, bus

    1. Fly from Louisville International Airport (SDF) to Gulfport-Biloxi Regional Airport (GPT)plane plane SDF - GPT
    2. Take the bus from Gulfport to Mobilebus bus
    7h 42m
    $164–684

  7. Bus (Greyhound)

    1. Take the bus from Louisville Bus Station to Montgomery Intermodal Centerbus bus Greyhound US0112
    2. Take the bus from Montgomery Intermodal Center to Mobile Bus Stationbus bus Greyhound US0602 / ...
    15h 36m
    $104–167

Louisville to Mobile by bus

Calendar14Weekly Buses
Duration13h 55mAverage Duration
Ticket$92Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Mobile.ExpandLaunch map view
  • Distance: 557.5 mi
  • Duration: 5h 44m

What companies run services between Louisville, KY, USA and Mobile, AL, USA?

Delta, American Airlines, and United Airlines fly from Louisville International Airport (SDF) to Mobile Regional Airport (MOB) every 2 hours. Alternatively, you can take a bus from Louisville Bus Station to Govt EB at Franklin St via Nashville Bus Station, Montgomery Intermodal Center, Mobile Bus Station, and Govt EB at Greyhound Bus Station in around 13h 55m.

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