There are 7 ways to get from Louisville to Myrtle Beach by plane, bus (Amtrak, Greyhound, Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Louisville International Airport
best- Fly from Louisville International Airport (SDF) to Myrtle Beach (MYR)plane SDF - MYR
4h 54m$78–377Bus via Atlanta
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
18h 10m$128–241Drive 609.3 mi
- Drive from Louisville to Myrtle Beachcar 609.3 mi
12h 31m$112–161Drive to Blue Grass Airport, fly
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Myrtle Beach (MYR)plane LEX - MYR
5h 14m$94–453Bus to Covington, fly
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus
- Fly from Covington (CVG) to Myrtle Beach (MYR)plane CVG - MYR
5h 19m$463–709Bus to Nashville, fly
- Take the bus from Louisville, KY to Nashvillebus
- Fly from Nashville (BNA) to Myrtle Beach (MYR)plane BNA - MYR
6h 15m$106–402Bus
- Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus
- Take the bus from Columbus - Mound St to Hurricanebus
- Take the bus from Hurricane to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
23h 5m$95–253
Louisville to Myrtle Beach by bus
Questions & Answers
The cheapest way to get from Louisville to Myrtle Beach is to drive which costs $110 - $170 and takes 12h 31m.
The fastest way to get from Louisville to Myrtle Beach is to fly which takes 4h 54m and costs $75 - $380.
No, there is no direct bus from Louisville to Myrtle Beach station. However, there are services departing from Louisville, KY and arriving at Myrtle Beach Bus Station via Nashville Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 18h 10m.
The distance between Louisville and Myrtle Beach is 504 miles. The road distance is 612.8 miles.
The best way to get from Louisville to Myrtle Beach without a car is to bus via Atlanta which takes 18h 10m and costs $120 - $250.
It takes approximately 4h 54m to get from Louisville to Myrtle Beach, including transfers.
Louisville to Myrtle Beach bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
The best way to get from Louisville to Myrtle Beach is to fly which takes 4h 54m and costs $75 - $380. Alternatively, you can bus via Atlanta, which costs $120 - $250 and takes 18h 10m.
Louisville to Myrtle Beach bus services, operated by Amtrak Thruway, arrive at Nashville station.
Yes, the driving distance between Louisville to Myrtle Beach is 613 miles. It takes approximately 12h 31m to drive from Louisville to Myrtle Beach.
What companies run services between Louisville, KY, USA and Myrtle Beach, SC, USA?
Southwest Airlines, American Airlines, and Delta fly from Louisville International Airport (SDF) to Myrtle Beach (MYR) every 4 hours. Alternatively, you can take a bus from Louisville, KY to Myrtle Beach Bus Station via Nashville Bus Station and Atlanta Bus Station in around 18h 10m.
- Website
- aa.com
Flights from Louisville International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $65–360
Flights from Blue Grass Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $70–420
Flights from Covington to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 38m
- When
- Monday to Saturday
- Estimated price
- $75–410
Flights from Nashville to Myrtle Beach via Charlotte
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $60–350
- Website
- southwest.com
Flights from Louisville International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 5h 14m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $70–390
Flights from Nashville to Myrtle Beach
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $60–340
- Website
- delta.com
Flights from Louisville International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $75–390
Flights from Blue Grass Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $90–470
Flights from Covington to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $90–470
Flights from Nashville to Myrtle Beach via Atlanta
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $65–360
- Website
- allegiantair.com
Flights from Covington to Myrtle Beach
- Ave. Duration
- 1h 32m
- When
- Thursday, Saturday, Sunday, Monday, and Friday
- Estimated price
- $70–410
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
Bus from Camden to Myrtle Beach Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $19–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
Bus from Louisville, KY Bus Station to Columbus - Downtown - Mound St
- Ave. Duration
- 4h 25m
- Frequency
- Twice daily
- Estimated price
- $21–60
- Website
- https://baronsbus.com
Bus from Columbus - Mound St to Hurricane
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $15–55
- Website
- https://baronsbus.com
Bus from Hurricane to Charlotte Bus Station
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $28–75
- Website
- https://baronsbus.com
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