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How to get fromLouisville to New Orleansby plane, bus (Amtrak, Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Louisville to New Orleans by plane, bus (Amtrak, Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Louisville International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Louis Armstrong New Orleans International Airport (MSY)plane plane SDF - MSY
    4h 38m
    $223–706

  2. Bus via Montgomery

    cheapest
    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Montgomery Intermodal Centerbus bus
    3. Take the bus from Montgomery Intermodal Center to New Orleans Bus Stationbus bus
    16h 50m
    $118–226

  3. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    3. Take the train from Champaign-Urbana to New Orleans Union Passenger Terminaltrain train
    23h 17m
    $301–629

  4. Drive 704.8 mi

    1. Drive from Louisville to New Orleanscar car 704.8 mi
    11h 27m
    $129–186

  5. Drive to Blue Grass Airport, fly

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Louis Armstrong New Orleans International Airport (MSY)plane plane LEX - MSY
    6h 31m
    $154–772

  6. Bus

    1. Take the bus from La Tropicana - Louisville, KY to El Mezcal Grocery - Jackson, TNbus bus
    2. Take the bus from Jackson to Memphis - Summer Avebus bus Nyc
    3. Take the bus from Memphis Bus Station to New Orleans Bus Stationbus bus
    22h 13m
    $158–349

Louisville to New Orleans by bus

Calendar14Weekly Buses
Duration16h 50mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from Louisville to New Orleans.ExpandLaunch map view
  • Distance: 641.5 mi
  • Duration: 4h 38m

What companies run services between Louisville, KY, USA and New Orleans, LA, USA?

Breeze Airways, Southwest Airlines, and Delta fly from Louisville International Airport (SDF) to Louis Armstrong New Orleans International Airport (MSY) 5 times a day. Alternatively, you can take a bus from Louisville, KY to New Orleans Bus Station via Nashville Bus Station and Montgomery Intermodal Center in around 16h 50m.

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