There are 11 ways to get from Louisville to Niagara Falls by plane, bus, bus (Amtrak), train, car, or bus (Amtrak, Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Buffalo Niagara International Airport, bus
best- Fly from Louisville International Airport (SDF) to Buffalo Niagara International Airport (BUF)plane SDF - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
6h 58m$126–710Bus via Cleveland
cheapest- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Toledobus
- Take the bus from Toledo to Clevelandbus
- Take the bus from Cleveland to Buffalobus
15h 33m$75–216Bus, train
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Toledobus
- Take the train from Toledo to Buffalo Depew Stationtrain
- Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain
15h 38m$212–509Drive 551.5 mi
- Drive from Louisville to Niagara Fallscar 551.5 mi
9h 27m$101–146Drive to Covington, fly to Toronto Pearson International Airport, bus
- Drive from Louisville to Covington (CVG)car
- Fly from Covington (CVG) to Toronto Pearson International Airport (YYZ)plane CVG - YYZ
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
5h 49m$101–530Fly Louisville International Airport to Toronto Pearson International Airport, bus
- Fly from Louisville International Airport (SDF) to Toronto Pearson International Airport (YYZ)plane SDF - YYZ
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
9h 14m$86–498Fly Louisville International Airport to Toronto Island Airport, bus
- Fly from Louisville International Airport (SDF) to Toronto Island Airport (YTZ)plane SDF - YTZ
- Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus
9h 31m$100–559Bus to Nashville, fly to Buffalo Niagara International Airport, bus
- Take the bus from Louisville, KY to Nashvillebus
- Fly from Nashville (BNA) to Buffalo Niagara International Airport (BUF)plane BNA - BUF
- Take the bus from Buffalo Niagara International Airport to Niagara Falls USAbus
8h 14m$149–755Bus, train via Ellicott Street & MTC Static
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Toledo Bus Stopbus
- Take the train from Toledo to Buffalo Depew Stationtrain
17h 30m$224–360Bus
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Columbusbus
- Take the bus from Columbus to Buffalobus
17h 48m$101–174Bus, train #2
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the train from Indianapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain
- Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain
21h 44m$411–814
Louisville to Niagara Falls by bus
Comparing Your Travel Options
The cheapest way to get from Louisville to Niagara Falls is to drive which costs $100 - $150 and takes 9h 27m.
The fastest way to get from Louisville to Niagara Falls is to drive and fly and bus which takes 5h 49m and costs $100 - $550.
No, there is no direct bus from Louisville to Niagara Falls. However, there are services departing from Louisville, KY and arriving at Main Street & Pine Avenue via Indianapolis, Toledo, Cleveland and Ellicott Street & MTC Static. The journey, including transfers, takes approximately 15h 33m.
The distance between Louisville and Niagara Falls is 534 miles. The road distance is 554.8 miles.
The best way to get from Louisville to Niagara Falls without a car is to bus via Cleveland which takes 15h 33m and costs $75 - $220.
It takes approximately 6h 58m to get from Louisville to Niagara Falls, including transfers.
Louisville to Niagara Falls bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Niagara Falls bus services, operated by Amtrak Thruway, arrive at Indianapolis Union Station.
Yes, the driving distance between Louisville to Niagara Falls is 555 miles. It takes approximately 9h 27m to drive from Louisville to Niagara Falls.
Book your Louisville to Niagara Falls bus tickets online with Omio.
What companies run services between Louisville, KY, USA and Niagara Falls, NY, USA?
You can take a bus from Louisville, KY to Main Street & Pine Avenue via Indianapolis, Toledo, Cleveland, and Ellicott Street & MTC Static in around 15h 33m.
- Website
- southwest.com
Flights from Louisville International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $140–800
Flights from Louisville International Airport to Buffalo Niagara International Airport via Chicago Midway
- Ave. Duration
- 6h 8m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $140–800
Flights from Louisville International Airport to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 6h 5m
- When
- Saturday to Sunday
- Estimated price
- $150–800
Flights from Nashville to Buffalo Niagara International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $110–700
Flights from Nashville to Buffalo Niagara International Airport via Chicago Midway
- Ave. Duration
- 3h 57m
- When
- Sunday, Saturday, Tuesday, and Wednesday
- Estimated price
- $140–750
Flights from Nashville to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 2m
- When
- Sunday
- Estimated price
- $140–750
- Website
- united.com
Flights from Louisville International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $140–800
Flights from Covington to Toronto Pearson International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $70–440
Flights from Louisville International Airport to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $90–500
Flights from Louisville International Airport to Toronto Pearson International Airport via Chicago O'Hare
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $85–480
Flights from Louisville International Airport to Toronto Island Airport via Washington Dulles
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $95–550
Flights from Louisville International Airport to Toronto Island Airport via Chicago O'Hare
- Ave. Duration
- 6h 23m
- When
- Sunday
- Estimated price
- $90–500
Flights from Louisville International Airport to Toronto Island Airport via New York La Guardia
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $110–600
- Website
- aa.com
Flights from Louisville International Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $160–850
Flights from Louisville International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
Flights from Louisville International Airport to Toronto Pearson International Airport via Chicago O'Hare
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $85–480
Flights from Louisville International Airport to Toronto Pearson International Airport via Charlotte
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Toronto Pearson International Airport via Reagan Washington
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $95–500
- Website
- aircanada.com
Flights from Covington to Toronto Pearson International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $70–440
Flights from Louisville International Airport to Toronto Pearson International Airport via Washington Dulles
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $90–500
Flights from Louisville International Airport to Toronto Pearson International Airport via Chicago O'Hare
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $85–480
Flights from Louisville International Airport to Toronto Island Airport via Chicago O'Hare
- Ave. Duration
- 6h 23m
- When
- Sunday
- Estimated price
- $90–500
Flights from Louisville International Airport to Toronto Island Airport via New York La Guardia
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $110–600
- Website
- delta.com
Flights from Louisville International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $120–700
Flights from Louisville International Airport to Toronto Pearson International Airport via Detroit
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $70–430
Flights from Nashville to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $120–700
Flights from Nashville to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
- Website
- flyporter.com
Flights from Louisville International Airport to Toronto Island Airport via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Sunday
- Estimated price
- $230–1,000
Flights from Louisville International Airport to Toronto Island Airport via Boston
- Ave. Duration
- 6h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Louisville International Airport to Toronto Island Airport via Newark
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $110–550
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Buffalo Depew Station
- Ave. Duration
- 5h 22m
- Frequency
- Twice daily
- Estimated price
- $160–250
- Website
- Amtrak
Train from Buffalo Depew Station to Niagara Falls Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 3 times a day
- Estimated price
- $18–29
- Website
- Amtrak
Train from Toledo to Buffalo Depew Station
- Ave. Duration
- 5h 22m
- Frequency
- Twice daily
- Estimated price
- $160–250
- Website
- Amtrak
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $100–170
- Website
- Amtrak
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $280–450
- Website
- Amtrak
Train from Buffalo Depew Station to Niagara Falls Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 3 times a day
- Estimated price
- $18–29
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo Depew Station to Niagara Falls Amtrak Station
- Ave. Duration
- 1h 23m
- Frequency
- Once daily
- Estimated price
- $8–150
- Website
- VIA Rail
- Escape
- $8–50
- Business
- $35–130
- Business Plus
- $50–150
- Economy
- $9–55
- Economy Plus
- $10–60
Train from Buffalo Depew Station to Niagara Falls Amtrak Station
- Ave. Duration
- 1h 23m
- Frequency
- Once daily
- Estimated price
- $8–150
- Website
- VIA Rail
- Escape
- $8–50
- Business
- $35–130
- Business Plus
- $50–150
- Economy
- $9–55
- Economy Plus
- $10–60
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $4–7
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Niagara Falls USA
- Ave. Duration
- 50 min
- Frequency
- Every 4 hours
- Estimated price
- $4–7
- Schedules at
- Flixbus USA
Bus from Columbus to Buffalo
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $45–75
- Schedules at
- Flixbus USA
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Louisville, KY to Nashville
- Ave. Duration
- 2h 55m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Indianapolis to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
Bus from Toledo to Cleveland
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $11–45
- Website
- Barons Bus
Bus from Cleveland to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- Barons Bus
Bus from Indianapolis to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
- Phone
- +1 866 488 4452
- [email protected]
- Website
- Megabus
Bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminal
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $16–55
Bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminal
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $16–55
Bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminal
- Ave. Duration
- 1h 35m
- Frequency
- Hourly
- Estimated price
- $7–55
- Website
- Megabus
- Adult Advanced Booking
- $7–45
- Adult Standard
- $16–55
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to Toledo Bus Stop
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Indianapolis Union Station to Columbus
- Ave. Duration
- 5h 5m
- Frequency
- 3 times a day
- Estimated price
- $29–50
- Website
- Greyhound
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