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How to get fromLouisville to North Carolinaby plane, bus (Amtrak, Greyhound, Flixbus), car, or bus (Greyhound)

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There are 7 ways to get from Louisville to North Carolina by plane, bus (Amtrak, Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Charlotte Douglas International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT)plane plane SDF - CLT
    3h 45m
    $95–606

  2. Drive 437.4 mi

    cheapest
    1. Drive from Louisville to Charlottecar car 437.4 mi
    9h 4m
    $80–116

  3. Bus

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    13h 30m
    $103–191

  4. Drive to Blue Grass Airport, fly to Charlotte Douglas International Airport

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Charlotte Douglas International Airport (CLT)plane plane LEX - CLT
    3h 37m
    $116–722

  5. Fly Louisville International Airport to Raleigh-Durham International Airport

    1. Fly from Louisville International Airport (SDF) to Raleigh-Durham International Airport (RDU)plane plane SDF - RDU
    4h 24m
    $85–486

  6. Bus via Atlanta

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus
    13h 49m
    $106–189

  7. Bus #2

    1. Take the bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus bus Louisville
    2. Take the bus from Wilson & Ferrell Shell Station - Columbus to Charlotte Bus Stationbus bus Greyhound US0140
    16h 20m
    $95–208

Louisville to North Carolina by bus

Calendar14Weekly Buses
Duration13h 30mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

Map of how to get from Louisville to North Carolina.ExpandLaunch map view
  • Distance: 349.5 mi
  • Duration: 3h 45m

What companies run services between Louisville, KY, USA and North Carolina, USA?

American Airlines and Southwest Airlines fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT) 5 times a day. Alternatively, you can take a bus from Louisville, KY to Charlotte Bus Station via Nashville Bus Station and Atlanta Bus Station in around 13h 30m.

Airlines
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