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How to get fromLouisville to North Charlestonby plane, bus (Amtrak, Greyhound, Flixbus), car, or bus (Greyhound)

Find Transport to North Charleston

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There are 4 ways to get from Louisville to North Charleston by plane, bus (Amtrak, Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Louisville International Airport (SDF) to Charleston International Airport (CHS)plane plane SDF - CHS
    4h 9m
    $344–405

  2. Bus

    cheapest
    1. Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus bus
    2. Take the bus from Columbus - Mound St to Hurricanebus bus
    3. Take the bus from Hurricane to Charlotte Bus Stationbus bus
    4. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus
    23h 25m
    $104–274

  3. Bus via Atlanta

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus
    20h 50m
    $138–261

  4. Drive 574.4 mi

    1. Drive from Louisville to North Charlestoncar car 574.4 mi
    11h 11m
    $105–152

Louisville to North Charleston by bus

Calendar7Weekly Buses
Duration20h 50mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from Louisville to North Charleston.ExpandLaunch map view
  • Distance: 500.4 mi
  • Duration: 4h 9m

What companies run services between Louisville, KY, USA and North Charleston, SC, USA?

Breeze Airways, Southwest Airlines, and two other airlines fly from Louisville International Airport (SDF) to Charleston International Airport (CHS) 5 times a day. Alternatively, you can take a bus from Louisville, KY to Charleston Bus Station via Nashville Bus Station and Atlanta Bus Station in around 20h 50m.

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Bus operators

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