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How to get fromLouisville to Pittsburghby plane, bus, bus (Greyhound), car, or bus (Flixbus)

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There are 4 ways to get from Louisville to Pittsburgh by plane, bus, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly, bus

    best
    1. Fly from Louisville International Airport (SDF) to Pittsburgh International Airport (PIT)plane plane SDF - PIT
    2. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    4h 17m
  2. Bus

    cheapest
    1. Take the bus from Louisville to Cincinnatibus bus Bsb 28 / ...
    2. Take the bus from Cincinnati to Pittsburgh Intermodal Stationbus bus FlixBus N2642
    9h 38m
    $52–119
  3. Bus via Columbus

    1. Take the bus from Louisville to Columbusbus bus Bsb 28 / ...
    2. Take the bus from Columbus to Pittsburgh Intermodal Stationbus bus Greyhound US0421
    8h 55m
    $55–107
  4. Drive  385.1 mi

    1. Drive from Louisville to Pittsburghcar car 385.1 mi
    6h 36m
    $71–102

Louisville to Pittsburgh by bus

Calendar21Weekly Buses
Duration8h 55mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between Louisville, KY, USA and Pittsburgh, PA, USA?

You can take a bus from Louisville to Pittsburgh Intermodal Station via Columbus in around 8h 55m.

Airlines
Bus operators

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