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How to get fromLouisville to Portlandby plane, bus, train, car, or bus (Amtrak, Greyhound, Flixbus)

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There are 8 ways to get from Louisville to Portland by plane, bus, train, car, or bus (Amtrak, Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Portland

    best
    1. Fly from Louisville International Airport (SDF) to Portland (PWM)plane plane SDF - PWM
    5h 28m
    $122–603

  2. Fly Louisville International Airport to Boston Logan Airport, bus

    cheapest
    1. Fly from Louisville International Airport (SDF) to Boston Logan Airport (BOS)plane plane SDF - BOS
    2. Take the bus from Logan International Airport to Portland, MEbus bus
    6h 46m
    $119–513

  3. Bus via Columbus

    1. Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus bus
    2. Take the bus from Columbus, OH to New York, NYbus bus
    3. Take the bus from New York, NY to Portland, MEbus bus
    22h 32m
    $199–272

  4. Bus, train via Cleveland

    1. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus bus
    2. Take the train from Cleveland Amtrak to Bostontrain train
    3. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    25h 25m
    $269–578

  5. Drive 1,035.9 mi

    1. Drive from Louisville to Portlandcar car 1,035.9 mi
    18h 33m
    $190–274

  6. Bus to Covington, fly to Portland

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Portland (PWM)plane plane CVG - PWM
    5h 57m
    $152–1,445

  7. Bus

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York Midtown to City of Portlandbus bus
    31h 32m
    $193–374

  8. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    4. Take the bus from Boston, MA - South Station to Portland, MEbus bus
    32h 11m
    $414–899

Louisville to Portland by bus and foot

Calendar7Weekly Services
Duration22h 32mAverage Duration
Ticket$199Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Portland.ExpandLaunch map view
  • Distance: 894.3 mi
  • Duration: 5h 28m

What companies run services between Louisville, KY, USA and Portland, ME, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to Portland (PWM) every 4 hours. Alternatively, you can take a bus from Louisville, KY Bus Station to Portland, ME via Columbus - Downtown - Mound St, Columbus, OH, New York, NY, Pike St/Division St, 1 Av/E 42 St, and New York, NY in around 22h 32m.

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