There are 7 ways to get from Louisville to Presque Isle by car, plane, bus (Amtrak, Flixbus), bus, train, or bus (Amtrak, Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Covington, fly
best- Drive from Louisville to Covington (CVG)car
- Fly from Covington (CVG) to Presque Isle (PQI)plane CVG - PQI
6h 19m$183–832Bus to Indianapolis, fly
cheapest- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Fly from Indianapolis (IND) to Presque Isle (PQI)plane IND - PQI
9h 58m$160–667Bus via Toledo
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Toledobus
- Take the bus from Toledo Bus Stop to New York Midtownbus
- Take the bus from New York Midtown to Bostonbus
- Take the bus from Boston, MA - South Station to Bangor Transportation Centerbus
- Take the bus from Bangor, ME to Presque Isle, Mainebus
34h 34m$240–429Bus, train via Toledo
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis to Toledobus
- Take the train from Toledo to Bostontrain
- Take the bus from Boston, MA - South Station to Bangor Transportation Centerbus
- Take the bus from Bangor, ME to Presque Isle, Mainebus
34h 42m$540–914Drive 1,259.7 mi
- Drive from Louisville to Presque Islecar 1,259.7 mi
23h 19m$216–311Bus
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Bostonbus
- Take the bus from Boston, MA - South Station to Bangor Transportation Centerbus
- Take the bus from Bangor, ME to Presque Isle, Mainebus
36h 55m$259–434Bus, train
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain
- Take the bus from Boston, MA - South Station to Bangor Transportation Centerbus
- Take the bus from Bangor, ME to Presque Isle, Mainebus
39h 23m$709–1,149
Louisville to Presque Isle by bus
Comparing Your Travel Options
The cheapest way to get from Louisville to Presque Isle is to drive which costs $210 - $320 and takes 23h 19m.
The fastest way to get from Louisville to Presque Isle is to drive and fly which takes 6h 19m and costs $180 - $850.
No, there is no direct bus from Louisville to Presque Isle. However, there are services departing from Louisville, KY and arriving at Presque Isle, Maine via Indianapolis, Toledo Bus Stop, New York Midtown, Boston, MA - South Station and Bangor, ME. The journey, including transfers, takes approximately 34h 34m.
The distance between Louisville and Presque Isle is 1093 miles. The road distance is 1267 miles.
The best way to get from Louisville to Presque Isle without a car is to bus via Toledo which takes 34h 34m and costs $240 - $430.
It takes approximately 6h 19m to get from Louisville to Presque Isle, including transfers.
Louisville to Presque Isle bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Presque Isle bus services, operated by Amtrak Thruway, arrive at Indianapolis Union Station.
Yes, the driving distance between Louisville to Presque Isle is 1267 miles. It takes approximately 23h 19m to drive from Louisville to Presque Isle.
There are 18+ hotels available in Presque Isle.
What companies run services between Louisville, KY, USA and Presque Isle, ME, USA?
You can take a bus from Louisville, KY to Presque Isle, Maine via Indianapolis, Toledo Bus Stop, New York Midtown, Boston, Boston, MA - South Station, Bangor Transportation Center, and Bangor, ME in around 34h 34m.
- Website
- jetblue.com
Flights from Covington to Presque Isle via Boston
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $160–800
Flights from Covington to Presque Isle via Detroit, Boston
- Ave. Duration
- 8h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–850
Flights from Indianapolis to Presque Isle via Boston
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $120–600
Flights from Indianapolis to Presque Isle via Baltimore, Boston
- Ave. Duration
- 6h 52m
- When
- Saturday
- Estimated price
- $120–600
Flights from Indianapolis to Presque Isle via Detroit, Boston
- Ave. Duration
- 7h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Boston
- Ave. Duration
- 17h 1m
- Frequency
- Once daily
- Estimated price
- $430–700
- Website
- Amtrak
Train from Indianapolis to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 22h 8m
- Frequency
- 3 times a week
- Estimated price
- $500–800
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 21m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 47m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Boston, MA - South Station to Bangor Transportation Center
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $43–48
- Website
- Amtrak
- Adult
- $43–48
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Boston, MA - South Station to Bangor Transportation Center
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $43–48
- Website
- Amtrak
- Adult
- $43–48
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Boston, MA - South Station to Bangor Transportation Center
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $43–48
- Website
- Amtrak
- Adult
- $43–48
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Boston, MA - South Station to Bangor Transportation Center
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $43–48
- Website
- Amtrak
- Adult
- $43–48
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Indianapolis to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
Bus from Indianapolis to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Toledo Bus Stop to New York Midtown
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- $100–160
- Schedules at
- Flixbus USA
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
Bus from Newark Penn Station to Boston
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
- Phone
- +1 800 639 3317
- [email protected]
- Website
- Concord Coach Lines
Bus from Boston, MA - South Station to Bangor Transportation Center
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $50–70
- Website
- Concord Coach Lines
Bus from Boston, MA - South Station to Bangor Transportation Center
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $50–70
- Website
- Concord Coach Lines
Bus from Boston, MA - South Station to Bangor Transportation Center
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $50–70
- Website
- Concord Coach Lines
Bus from Boston, MA - South Station to Bangor Transportation Center
- Ave. Duration
- 4h 10m
- Frequency
- Every 4 hours
- Estimated price
- $50–70
- Website
- Concord Coach Lines
- Phone
- +1 207-827-2335
- [email protected]
- Website
- Cyr Bus Line
Bus from Bangor, ME to Presque Isle, Maine
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $26–35
- Website
- Cyr Bus Line
- Adult One-way
- $26–35
Bus from Bangor, ME to Presque Isle, Maine
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $26–35
- Website
- Cyr Bus Line
- Adult One-way
- $26–35
Bus from Bangor, ME to Presque Isle, Maine
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $26–35
- Website
- Cyr Bus Line
- Adult One-way
- $26–35
Bus from Bangor, ME to Presque Isle, Maine
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $26–35
- Website
- Cyr Bus Line
- Adult One-way
- $26–35
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to Newark Penn Station
- Ave. Duration
- 18h 15m
- Frequency
- 4 times a day
- Estimated price
- $130–210
- Website
- Greyhound
Bus from Newark Penn Station to Boston
- Ave. Duration
- 5h 5m
- Frequency
- Every 3 hours
- Estimated price
- $45–75
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide












