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How to get fromLouisville to Roanokeby plane, bus (Greyhound, Amtrak, Flixbus), bus, train, car, or bus (Greyhound)

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There are 5 ways to get from Louisville to Roanoke by plane, bus (Greyhound, Amtrak, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Louisville International Airport (SDF) to Roanoke Regional Airport-Woodrum Field (ROA)plane plane SDF - ROA
    6h 13m
    $81–468

  2. Drive  414.7 mi

    cheapest
    1. Drive from Louisville to Roanokecar car 414.7 mi
    7h 16m
    $76–110

  3. Bus

    1. Take the bus from Louisville Bus Station to Nashville Bus Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus Greyhound US0600
    12h 20m
    $91–166

  4. Bus, train

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Charlottesvilletrain train
    3. Take the train from Charlottesville to Roanoketrain train
    21h 48m
    $212–469

  5. Bus via Preston @ Park Brook

    1. Take the bus from La Tropicana - Louisville, KY to Tornado Bus Co - Nashvillebus bus Indianapolis
    2. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus Greyhound US0600
    14h 56m
    $106–187

Louisville to Roanoke by bus

Calendar7Weekly Buses
Duration12h 20mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Roanoke.ExpandLaunch map view
  • Distance: 334.6 mi
  • Duration: 6h 13m

What companies run services between Louisville, KY, USA and Roanoke, VA, USA?

American Airlines, United Airlines, and Delta fly from Louisville International Airport (SDF) to Roanoke Regional Airport-Woodrum Field (ROA) hourly. Alternatively, you can take a bus from Louisville Bus Station to Roanoke Bus Stop via Nashville Bus Station in around 12h 20m.

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