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How to get fromLouisville to Rochesterby plane, bus, train, car, or bus (Greyhound, Flixbus)

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There are 9 ways to get from Louisville to Rochester by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Rochester

    best
    1. Fly from Louisville International Airport (SDF) to Rochester (ROC)plane plane SDF - ROC
    5h 19m
    $177–922

  2. Bus

    cheapest
    1. Take the bus from Louisville Bus Station to Cincinnati Bus Stationbus bus
    2. Take the bus from Cincinnati, OH to Buffalo, NYbus bus
    3. Take the bus from Buffalo to Rochester Bus Stopbus bus
    14h 35m
    $67–158

  3. Bus, train via Cleveland

    1. Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus bus Louisville / ...
    2. Take the train from Cleveland Amtrak to Rochestertrain train Lake Shore Limited
    12h 38m
    $98–233

  4. Bus, train

    1. Take the bus from Louisville Bus Station to Toledo Bus Stopbus bus Greyhound US0135 / ...
    2. Take the train from Toledo to Rochestertrain train Lake Shore Limited
    13h 54m
    $138–285

  5. Drive  595.3 mi

    1. Drive from Louisville to Rochestercar car 595.3 mi
    10h 22m
    $109–157

  6. Drive to Blue Grass Airport, fly to Rochester

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to Rochester (ROC)plane plane LEX - ROC
    5h 37m
    $148–738

  7. Fly Louisville International Airport to Buffalo Niagara International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Buffalo Niagara International Airport (BUF)plane plane SDF - BUF
    2. Take the bus from Buffalo Niagara International Airport to Rochester Bus Stopbus bus
    7h 13m
    $131–718

  8. Bus to Covington, fly to Rochester

    1. Take the bus from Louisville to Cincinnatibus bus
    2. Fly from Covington (CVG) to Rochester (ROC)plane plane CVG - ROC
    7h 25m
    $187–1,014

  9. Bus via Akron

    1. Take the bus from Louisville to Akronbus bus
    2. Take the bus from Akron to Buffalobus bus
    3. Take the bus from Buffalo to Rochesterbus bus 325
    14h 10m
    $73–192

Louisville to Rochester by bus, foot, and train

Calendar14Weekly Services
Duration12h 38mAverage Duration
Ticket$98Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Rochester.ExpandLaunch map view
  • Distance: 553.8 mi
  • Duration: 5h 19m

What companies run services between Louisville, KY, USA and Rochester, NY, USA?

United Airlines, Delta, and two other airlines fly from Louisville International Airport (SDF) to Rochester (ROC) hourly. Alternatively, you can take a bus from Louisville to Rochester via Akron and Buffalo in around 14h 10m.

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