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How to get fromLouisville to Saint Paulby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Amtrak)

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There are 6 ways to get from Louisville to Saint Paul by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Louisville International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Minneapolis–Saint Paul International Airport (MSP)plane plane SDF - MSP
    4h 14m
    $104–556

  2. Bus

    1. Take the bus from Louisville Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    2. Take the bus from Chicago Bus Station to Saint Paul Union Depotbus bus Greyhound US0150
    14h 45m
    $106–217

  3. Bus, train

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    16h 26m
    $213–444

  4. Drive 693.1 mi

    1. Drive from Louisville to Saint Paulcar car 693.1 mi
    11h 32m
    $127–183

  5. Bus to Covington, fly

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to Minneapolis–Saint Paul International Airport (MSP)plane plane CVG - MSP
    6h 15m
    $814–1,548

  6. Bus via Madison

    1. Take the bus from Louisville, KY to Lafayette Amtrak Stationbus bus
    2. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Minneapolisbus bus
    19h 30m
    $145–248

Louisville to Saint Paul by bus

Calendar56Weekly Buses
Duration14h 45mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Saint Paul.ExpandLaunch map view
  • Distance: 616.6 mi
  • Duration: 4h 14m

What companies run services between Louisville, KY, USA and Saint Paul, MN, USA?

Delta, Southwest Airlines, and two other airlines fly from Louisville International Airport (SDF) to Minneapolis–Saint Paul International Airport (MSP) every 3 hours. Alternatively, you can take a bus from Louisville Bus Station to Saint Paul Union Depot via Chicago Bus Station in around 14h 45m.

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