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How to get fromLouisville to San Antonioby plane, bus (Amtrak, Greyhound, Flixbus), bus, train, or car

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There are 7 ways to get from Louisville to San Antonio by plane, bus (Amtrak, Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to San Antonio International Airport

    best
    1. Fly from Louisville International Airport (SDF) to San Antonio International Airport (SAT)plane plane SDF - SAT
    6h 29m
    $384–955

  2. Fly Louisville International Airport to Austin-Bergstrom International Airport, bus

    cheapest
    1. Fly from Louisville International Airport (SDF) to Austin-Bergstrom International Airport (AUS)plane plane SDF - AUS
    2. Take the bus from Austin Eastside Bus Plaza to San Antonio Bus Stationbus bus
    9h 4m
    $165–780

  3. Bus via Irving

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to San Antonio Bus Stationbus bus
    23h 10m
    $173–326

  4. Bus, train

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to San Antonio Stationtrain train
    34h 16m
    $383–801

  5. Drive 1,095.9 mi

    1. Drive from Louisville to San Antoniocar car 1,095.9 mi
    17h 48m
    $200–289

  6. Bus to Nashville, fly to San Antonio International Airport

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Fly from Nashville (BNA) to San Antonio International Airport (SAT)plane plane BNA - SAT
    7h 40m
    $487–1,550

  7. Bus

    1. Take the bus from La Tropicana - Louisville, KY to Tornado Bus Co - West Memphisbus bus Indianapolis
    2. Take the bus from Tornado Bus Co - West Memphis to Tornado Bus Co - San Antoniobus bus West Memphis / ...
    25h 28m
    $199–455

Louisville to San Antonio by bus

Calendar14Weekly Buses
Duration23h 10mAverage Duration
Ticket$173Cheapest Price
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Questions & Answers

Map of how to get from Louisville to San Antonio.ExpandLaunch map view
  • Distance: 957.8 mi
  • Duration: 6h 29m

What companies run services between Louisville, KY, USA and San Antonio, TX, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Louisville International Airport (SDF) to San Antonio International Airport (SAT) hourly. Alternatively, you can take a bus from Louisville, KY to San Antonio Bus Station via Nashville Bus Station and Dallas Bus Station in around 23h 10m.

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