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How to get fromLouisville to San Franciscoby plane, bus (Greyhound), bus, train, or car

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There are 9 ways to get from Louisville to San Francisco by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to San Francisco International Airport

    best
    1. Fly from Louisville International Airport (SDF) to San Francisco International Airport (SFO)plane plane SDF - SFO
    6h 59m
    $211–615

  2. Bus

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles Union Station to San Francisco Bus Stationbus bus
    2d 9h
    $403–771

  3. Bus, train (Amtrak)

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the train from Chicago Union Station to Richmondtrain train California Zephyr
    2d 12h
    $804–1,664

  4. Drive 2,306.4 mi

    1. Drive from Louisville to San Franciscocar car 2,306.4 mi
    36h 5m
    $421–608

  5. Fly Louisville International Airport to Oakland International Airport

    1. Fly from Louisville International Airport (SDF) to Oakland International Airport (OAK)plane plane SDF - OAK
    8h 21m
    $217–911

  6. Fly Louisville International Airport to Norman Y. Mineta San José International Airport, Caltrain

    1. Fly from Louisville International Airport (SDF) to Norman Y. Mineta San José International Airport (SJC)plane plane SDF - SJC
    2. Take the train from Santa Clara Caltrain Northbound to San Francisco Caltrain Northboundtrain train
    9h 33m
    $214–868

  7. Bus to Covington, fly to San Francisco International Airport

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to San Francisco International Airport (SFO)plane plane CVG - SFO
    9h 18m
    $261–657

  8. Bus to Nashville, fly to San Francisco International Airport

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Fly from Nashville (BNA) to San Francisco International Airport (SFO)plane plane BNA - SFO
    9h 43m
    $254–530

  9. Bus to Indianapolis, fly to San Francisco International Airport

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Fly from Indianapolis (IND) to San Francisco International Airport (SFO)plane plane IND - SFO
    9h 54m
    $332–824

Louisville to San Francisco by bus

Calendar7Weekly Buses
Duration2d 9hAverage Duration
Ticket$403Cheapest Price
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Questions & Answers

Map of how to get from Louisville to San Francisco.ExpandLaunch map view
  • Distance: 2,005.6 mi
  • Duration: 6h 59m

What companies run services between Louisville, KY, USA and San Francisco, CA, USA?

Breeze Airways, Southwest Airlines, and United Airlines fly from Louisville International Airport (SDF) to San Francisco International Airport (SFO) 5 times a day. Alternatively, you can take a bus from Louisville, KY to San Francisco Bus Station via Evansville Bus Station, St Louis Bus Station, and Los Angeles Union Station in around 2d 9h.

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