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How to get fromLouisville to San Luis Obispoby plane, bus (Greyhound, Flixbus), bus, train, or car

Find Transport to San Luis Obispo

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There are 9 ways to get from Louisville to San Luis Obispo by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to San Luis Obispo County Regional Airport

    best
    1. Fly from Louisville International Airport (SDF) to San Luis Obispo County Regional Airport (SBP)plane plane SDF - SBP
    10h 9m
    $143–605
  2. Bus

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus bus
    2d 5h
    $373–701
  3. Bus, train via Chicago (Amtrak)

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Luis Obispotrain train
    2d 9h
    $825–1,727
  4. Drive 2,209.5 mi

    1. Drive from Louisville to San Luis Obispocar car 2,209.5 mi
    35h 33m
    $404–583
  5. Drive to Blue Grass Airport, fly to San Luis Obispo County Regional Airport

    1. Drive from Louisville to Lexington-Airport-LEXcar car
    2. Fly from Blue Grass Airport (LEX) to San Luis Obispo County Regional Airport (SBP)plane plane LEX - SBP
    9h 34m
    $194–771
  6. Fly Louisville International Airport to Santa Barbara Municipal Airport, bus

    1. Fly from Louisville International Airport (SDF) to Santa Barbara Municipal Airport (SBA)plane plane SDF - SBA
    2. Take the bus from Uc Santa Barbara Amtrak Bus Stop to San Luis Obispobus bus
    11h 32m
    $193–755
  7. Bus to Covington, fly to San Luis Obispo County Regional Airport

    1. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    2. Fly from Covington (CVG) to San Luis Obispo County Regional Airport (SBP)plane plane CVG - SBP
    12h 2m
    $173–697
  8. Bus to Indianapolis, fly to San Luis Obispo County Regional Airport

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Fly from Indianapolis (IND) to San Luis Obispo County Regional Airport (SBP)plane plane IND - SBP
    12h 9m
    $174–664
  9. Bus, train

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Los Angelestrain train
    4. Take the train from Los Angeles to San Luis Obispotrain train
    3d 1h
    $883–1,851

Louisville to San Luis Obispo by bus

Calendar7Weekly Buses
Duration2d 5hAverage Duration
Ticket$373Cheapest Price
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Questions & Answers

What companies run services between Louisville, KY, USA and San Luis Obispo, CA, USA?

American Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to San Luis Obispo County Regional Airport (SBP) 4 times a day. Alternatively, you can take a bus from Louisville, KY to San Luis Obispo Railroad Museum via Evansville Bus Station, St Louis Bus Station, and Los Angeles Union Station in around 2d 5h.

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