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How to get fromLouisville to Santa Anaby plane, bus (Greyhound), bus, train, or car

Find Transport to Santa Ana

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There are 7 ways to get from Louisville to Santa Ana by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Louisville International Airport (SDF) to John Wayne Airport Orange County (SNA)plane plane SDF - SNA
    7h 47m
    $241–988

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Louisville International Airport (SDF) to Los Angeles International Airport (LAX)plane plane SDF - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    10h 26m
    $147–636

  3. Bus

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to El Monte Bus Stopbus bus
    4. Take the bus from El Monte to Santa Anabus bus
    2d 1h
    $379–680

  4. Bus, train via Chicago

    1. Take the bus from Louisville Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    2d 4h
    $574–1,473

  5. Drive  2,070.4 mi

    1. Drive from Louisville to Santa Anacar car 2,070.4 mi
    32h 46m
    $378–546

  6. Fly to Long Beach Airport

    1. Fly from Louisville International Airport (SDF) to Long Beach Airport (LGB)plane plane SDF - LGB
    10h 48m
    $147–660

  7. Bus, train

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Pomona Amtraktrain train
    2d 20h
    $617–1,577

Louisville to Santa Ana by bus

Calendar7Weekly Buses
Duration2d 1hAverage Duration
Ticket$379Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Santa Ana.ExpandLaunch map view
  • Distance: 1,826.6 mi
  • Duration: 7h 47m

What companies run services between Louisville, KY, USA and Santa Ana, CA, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Louisville International Airport (SDF) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a bus from Louisville, KY to Santa Ana via Evansville Bus Station, St Louis Bus Station, El Monte Bus Stop, El Monte Station Upper Level, Garvey Ave and Mountain View Rd E, and El Monte in around 2d 1h.

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Need to know: Greyhound

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