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How to get fromLouisville to Santa Anaby plane, bus (Greyhound), bus, train, or car

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There are 9 ways to get from Louisville to Santa Ana by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to John Wayne Airport Orange County

    best
    1. Fly from Louisville International Airport (SDF) to John Wayne Airport Orange County (SNA)plane plane SDF - SNA
    9h 6m
    $144–655

  2. Fly Louisville International Airport to Los Angeles International Airport, train

    cheapest
    1. Fly from Louisville International Airport (SDF) to Los Angeles International Airport (LAX)plane plane SDF - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    8h 57m
    $118–456

  3. Bus

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to El Monte Bus Stopbus bus
    4. Take the bus from El Monte to Santa Anabus bus
    2d 1h
    $433–710

  4. Bus, train via Chicago (Amtrak)

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus Nashville
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d 2h
    $1,256–1,966

  5. Drive  2,070.4 mi

    1. Drive from Louisville to Santa Anacar car 2,070.4 mi
    32h 46m
    $342–494

  6. Drive to Covington, fly to Los Angeles International Airport, train

    1. Drive from Louisville to Covington (CVG)car car
    2. Fly from Covington (CVG) to Los Angeles International Airport (LAX)plane plane CVG - LAX
    3. Take the train from Los Angeles to Santa Anatrain train
    9h 14m
    $252–1,016

  7. Fly Louisville International Airport to Long Beach Airport

    1. Fly from Louisville International Airport (SDF) to Long Beach Airport (LGB)plane plane SDF - LGB
    10h 48m
    $137–610

  8. Fly Louisville International Airport to Ontario International Airport, train

    1. Fly from Louisville International Airport (SDF) to Ontario International Airport (ONT)plane plane SDF - ONT
    2. Take the train from San Bernardino Depot to Santa Anatrain train
    12h 31m
    $133–570

  9. Bus, train

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Pomona Amtraktrain train
    2d 20h
    $1,371–2,277

Louisville to Santa Ana by bus

Calendar7Weekly Buses
Duration2d 1hAverage Duration
Ticket$433Cheapest Price
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Comparing Your Travel Options

Map of how to get from Louisville to Santa Ana.ExpandLaunch map view
  • Distance: 1,826.2 mi
  • Duration: 9h 6m

What companies run services between Louisville, KY, USA and Santa Ana, CA, USA?

Southwest Airlines, American Airlines, and United Airlines fly from Louisville International Airport (SDF) to John Wayne Airport Orange County (SNA) every 3 hours. Alternatively, you can take a bus from Louisville, KY to Santa Ana via Evansville Bus Station, St Louis Bus Station, El Monte Bus Stop, El Monte Station Upper Level, Garvey Ave and Mountain View Rd E, and El Monte in around 2d 1h.

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Want to know more about travelling around United States

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Need to know: Greyhound

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