Rome2Rio

How to get fromLouisville to Santa Cruzby plane, bus, bus (Greyhound, Flixbus, Amtrak), train, car, or subway

Find Transport to Santa Cruz

See all options

There are 9 ways to get from Louisville to Santa Cruz by plane, bus, bus (Greyhound, Flixbus, Amtrak), train, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Norman Y. Mineta San José International Airport, bus

    best
    1. Fly from Louisville International Airport (SDF) to Norman Y. Mineta San José International Airport (SJC)plane plane SDF - SJC
    2. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    9h 25m
    $218–877

  2. Fly Louisville International Airport to Monterey Regional Airport

    cheapest
    1. Fly from Louisville International Airport (SDF) to Monterey Regional Airport (MRY)plane plane SDF - MRY
    13h 51m
    $181–771

  3. Bus

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    4. Take the bus from Los Angeles Union Station to San Jose Diridon Stationbus bus
    5. Take the bus from Diridon Station to Soquel Ave & Frontbus bus 17
    2d 8h
    $403–766

  4. Bus, train

    1. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    2. Take the train from Chicago Union Station to Emeryvilletrain train
    3. Take the train from Emeryville to San Josetrain train
    4. Take the bus from Diridon Station to Soquel Ave & Frontbus bus 17
    2d 15h
    $825–1,707

  5. Drive 2,328.7 mi

    1. Drive from Louisville to Santa Cruzcar car 2,328.7 mi
    37h 23m
    $425–614

  6. Fly Louisville International Airport to San Francisco International Airport, Caltrain, bus

    1. Fly from Louisville International Airport (SDF) to San Francisco International Airport (SFO)plane plane SDF - SFO
    2. Take the train from Millbrae Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    8h 54m
    $227–639

  7. Fly Louisville International Airport to Oakland International Airport, BART, bus

    1. Fly from Louisville International Airport (SDF) to Oakland International Airport (OAK)plane plane SDF - OAK
    2. Take the subway from Coliseum to Berryessa / North San Josesubway subway
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    10h 13m
    $232–935

  8. Bus to Nashville, fly to Norman Y. Mineta San José International Airport, bus

    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Fly from Nashville (BNA) to Norman Y. Mineta San José International Airport (SJC)plane plane BNA - SJC
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    11h 2m
    $241–872

  9. Bus to Indianapolis, fly to San Francisco International Airport, Caltrain, bus

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Fly from Indianapolis (IND) to San Francisco International Airport (SFO)plane plane IND - SFO
    3. Take the train from Millbrae Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train
    4. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    11h 49m
    $248–798

Louisville to Santa Cruz by bus

Calendar7Weekly Buses
Duration2d 8hAverage Duration
Ticket$403Cheapest Price
See schedules

Questions & Answers

Map of how to get from Louisville to Santa Cruz.ExpandLaunch map view
  • Distance: 2,008.4 mi
  • Duration: 9h 25m

What companies run services between Louisville, KY, USA and Santa Cruz, CA, USA?

You can take a bus from Louisville, KY to Soquel Ave & Front via Evansville Bus Station, St Louis Bus Station, Los Angeles Union Station, San Jose Diridon Station, and Diridon Station in around 2d 8h. Alternatively, American Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to Monterey Regional Airport (MRY) 4 times a day.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers