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How to get fromLouisville to Senecaby plane, taxi, bus, or car

Find Transport to Seneca

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There are 6 ways to get from Louisville to Seneca by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Louisville International Airport (SDF) to Greenville–Spartanburg International Airport (GSP)plane plane SDF - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    5h 35m
    $232–773

  2. Drive 385.1 mi

    cheapest
    1. Drive from Louisville to Senecacar car 385.1 mi
    8h 32m
    $71–102

  3. Bus, taxi

    1. Take the bus from Louisville Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    12h 52m
    $210–399

  4. Fly Louisville International Airport to Asheville Regional Airport, drive

    1. Fly from Louisville International Airport (SDF) to Asheville Regional Airport (AVL)plane plane SDF - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    6h 38m
    $79–422

  5. Fly Louisville International Airport to Hartsfield-Jackson Atlanta International Airport, bus, taxi

    1. Fly from Louisville International Airport (SDF) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane SDF - ATL
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    7h 28m
    $220–756

  6. Bus to Nashville, fly to Greenville–Spartanburg International Airport, taxi

    1. Take the bus from Louisville Bus Station to Nashville Bus Stationbus bus
    2. Fly from Nashville (BNA) to Greenville–Spartanburg International Airport (GSP)plane plane BNA - GSP
    3. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    6h 51m
    $240–775

Louisville International Airport (SDF) to Greenville–Spartanburg International Airport (GSP) flights

Calendar105Weekly Planes
Duration4h 16mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from Louisville to Seneca.ExpandLaunch map view
  • Distance: 356.1 mi
  • Duration: 5h 35m

What companies run services between Louisville, KY, USA and Seneca, SC, USA?

There is no direct connection from Louisville to Seneca. However, you can take the line 02 bus to Louisville International Airport, walk to Louisville International Airport (SDF) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take the bus to Atlanta Bus Station, walk to Garnett Station, take the subway to Doraville Station, walk to Atlanta, take the bus to Flying J - Commerce, then take the taxi to Seneca.

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