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How to get fromLouisville to Sikestonby bus, car, plane, or taxi

Find Transport to Sikeston

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There are 4 ways to get from Louisville to Sikeston by bus, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive

    best
    1. Take the bus from Louisville, KY to Nashvillebus bus
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    7h 42m
    $64–93

  2. Drive  275.7 mi

    cheapest
    1. Drive from Louisville to Sikestoncar car 275.7 mi
    4h 47m
    $51–73

  3. Fly, drive

    1. Fly from Louisville International Airport (SDF) to Barkley Regional Airport (PAH)plane plane SDF - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    6h 46m
    $102–568

  4. Bus, taxi

    1. Take the bus from Louisville, KY to Evansville, INbus bus
    2. Take the bus from Evansville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    10h 20m
    $173–318

Louisville International Airport (SDF) to Barkley Regional Airport (PAH) flights

Calendar21Weekly Planes
Duration4h 34mAverage Duration
Ticket$91Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Louisville to Sikeston.ExpandLaunch map view
  • Distance: 373.2 mi
  • Duration: 7h 42m

What companies run services between Louisville, KY, USA and Sikeston, MO, USA?

There is no direct connection from Louisville to Sikeston. However, you can take the bus to Nashville, take the bus to Paducah Bus Station, then drive to Sikeston. Alternatively, you can drive from Louisville to Sikeston in around 4h 47m.

Airlines
Bus operators
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