There are 8 ways to get from Louisville to Sumter by plane, bus, bus (Amtrak, Greyhound, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Louisville International Airport to Florence Regional Airport, bus
best- Fly from Louisville International Airport (SDF) to Florence Regional Airport (FLO)plane SDF - FLO
- Take the bus from Florence Bus Station to Sumter Bus Stopbus
7h 53m$89–449Fly Louisville International Airport to Columbia, bus
cheapest- Fly from Louisville International Airport (SDF) to Columbia (CAE)plane SDF - CAE
- Take the bus from Laurel Sumter East to James E Clyburn Intermodal Transportation Centerbus
8h 40m$76–427Bus via Atlanta
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Camdenbus
- Take the bus from Camden to Sumter Bus Stopbus
16h 25m$107–194Drive 514.7 mi
- Drive from Louisville to Sumtercar 514.7 mi
10h 31m$94–136Fly Louisville International Airport to Charlotte Douglas International Airport, bus
- Fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT)plane SDF - CLT
- Take the bus from Charlotte Bus Station to Sumter Bus Stopbus
7h 25m$111–639Drive to Blue Grass Airport, fly to Charlotte Douglas International Airport, bus
- Drive from Louisville to Lexington-Airport-LEXcar
- Fly from Blue Grass Airport (LEX) to Charlotte Douglas International Airport (CLT)plane LEX - CLT
- Take the bus from Charlotte Bus Station to Sumter Bus Stopbus
7h 17m$132–755Fly Louisville International Airport to Charleston International Airport, bus
- Fly from Louisville International Airport (SDF) to Charleston International Airport (CHS)plane SDF - CHS
- Take the bus from Charleston Bus Station to Sumter Bus Stopbus
10h 6m$370–452Bus
- Take the bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus
- Take the bus from Wilson & Ferrell Shell Station - Columbus to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Sumter Bus Stopbus
19h 55m$105–228
Louisville to Sumter by bus
Questions & Answers
The cheapest way to get from Louisville to Sumter is to drive which costs $90 - $140 and takes 10h 31m.
The fastest way to get from Louisville to Sumter is to drive and fly and bus which takes 7h 17m and costs $130 - $800.
No, there is no direct bus from Louisville to Sumter. However, there are services departing from Louisville, KY and arriving at Sumter Bus Stop via Nashville Bus Station, Atlanta Bus Station and Camden. The journey, including transfers, takes approximately 16h 25m.
The distance between Louisville and Sumter is 486 miles. The road distance is 517.7 miles.
The best way to get from Louisville to Sumter without a car is to bus via Atlanta which takes 16h 25m and costs $100 - $200.
It takes approximately 7h 53m to get from Louisville to Sumter, including transfers.
Louisville to Sumter bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Sumter bus services, operated by Amtrak Thruway, arrive at Nashville station.
Yes, the driving distance between Louisville to Sumter is 518 miles. It takes approximately 10h 31m to drive from Louisville to Sumter.
There are 22+ hotels available in Sumter.
What companies run services between Louisville, KY, USA and Sumter, SC, USA?
You can take a bus from Louisville, KY to Sumter Bus Stop via Nashville Bus Station, Atlanta Bus Station, and Camden in around 16h 25m.
- Website
- aa.com
Flights from Louisville International Airport to Florence Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 6h 48m
- When
- Every day
- Estimated price
- $70–420
Flights from Louisville International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $90–600
Flights from Blue Grass Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $100–700
Flights from Louisville International Airport to Columbia via Charlotte Douglas International Airport
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $70–420
Flights from Louisville International Airport to Columbia via Reagan Washington
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Columbia via Philadelphia
- Ave. Duration
- 5h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Louisville International Airport to Columbia via Chicago O'Hare
- Ave. Duration
- 5h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Louisville International Airport to Charleston International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $80–470
- Website
- delta.com
Flights from Blue Grass Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Friday and Sunday
- Estimated price
- $140–850
Flights from Louisville International Airport to Columbia via Atlanta
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $75–440
Flights from Louisville International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $85–490
- Website
- united.com
Flights from Louisville International Airport to Columbia via Washington Dulles
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Columbia via Chicago O'Hare
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $110–550
- Website
- southwest.com
Flights from Louisville International Airport to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–650
Flights from Louisville International Airport to Charleston International Airport via Nashville
- Ave. Duration
- 3h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $85–490
- Website
- flybreeze.com
Flights from Louisville International Airport to Charleston International Airport
- Ave. Duration
- 1h 38m
- When
- Monday and Friday
- Estimated price
- $340–400
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Florence Bus Station to Sumter Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $5–11
- Website
- Greyhound
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Atlanta Bus Station to Camden
- Ave. Duration
- 5h
- Frequency
- Twice daily
- Estimated price
- $35–70
- Website
- Greyhound
Bus from Camden to Sumter Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Once daily
- Estimated price
- $4–8
- Website
- Greyhound
Bus from Charlotte Bus Station to Sumter Bus Stop
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $15–30
- Website
- Greyhound
Bus from Charlotte Bus Station to Sumter Bus Stop
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $15–30
- Website
- Greyhound
Bus from Charleston Bus Station to Sumter Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $24–45
- Website
- Greyhound
Bus from Wilson & Ferrell Shell Station - Columbus to Charlotte Bus Station
- Ave. Duration
- 11h 20m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- Greyhound
Bus from Charlotte Bus Station to Sumter Bus Stop
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $15–30
- Website
- Greyhound
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
- Phone
- +1 803-255-7100
- Website
- The COMET
Bus from Laurel Sumter East to James E Clyburn Intermodal Transportation Center
- Ave. Duration
- 1h 28m
- Frequency
- Once daily
- Estimated price
- $2
- Schedules at
- The COMET
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbus
- Ave. Duration
- 4h
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- Barons Bus
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide










