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How to get fromLouisville to Winston-Salemby plane, bus (Greyhound), car, or bus

Find Transport to Winston-Salem

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There are 5 ways to get from Louisville to Winston-Salem by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Piedmont Triad International Airport (GSO)plane plane SDF - GSO
    6h 10m
    $131–676
  2. Drive 420.1 mi

    cheapest
    1. Drive from Louisville to Winston-Salemcar car 420.1 mi
    8h 8m
    $77–111
  3. Bus

    1. Take the bus from Louisville, KY Bus Station to Columbus - Downtown - Mound Stbus bus Louisville
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus Greyhound US0140
    14h 45m
    $99–194
  4. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Charlotte Douglas International Airport (CLT)plane plane SDF - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 15m
    $103–649
  5. Fly to Raleigh-Durham International Airport, bus

    1. Fly from Louisville International Airport (SDF) to Raleigh-Durham International Airport (RDU)plane plane SDF - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    7h 2m
    $100–493

Louisville to Winston-Salem by bus

Calendar14Weekly Buses
Duration14h 45mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

What companies run services between Louisville, KY, USA and Winston-Salem, NC, USA?

Delta, American Airlines, and United Airlines fly from Louisville International Airport (SDF) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Louisville, KY Bus Station to Winston Salem(Trans Center) via Columbus in around 14h 45m.

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