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How to get fromLowell to Florida Keysby plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

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There are 8 ways to get from Lowell to Florida Keys by plane, train, bus, car, shuttle, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Key West International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Key West International Airport (EYW)plane plane BOS - EYW
    8h 57m
    $188–591

  2. Train, bus to Manchester Airport, fly to Key West International Airport

    cheapest
    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Key West International Airport (EYW)plane plane MHT - EYW
    12h 45m
    $184–551

  3. Train, bus

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Newark Penn Stationtrain train
    3. Take the bus from Newark Penn Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    38h 52m
    $297–1,112

  4. Train, bus via New York

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    41h 23m
    $851–2,026

  5. Drive  1,628 mi

    1. Drive from Lowell to Florida Keyscar car 1,628 mi
    28h 33m
    $298–430

  6. Fly Boston Logan Airport to Miami International Airport, shuttle

    1. Fly from Boston Logan Airport (BOS) to Miami International Airport (MIA)plane plane BOS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    11h 12m
    $313–1,101

  7. Fly Boston Logan Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Boston Logan Airport (BOS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane BOS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    11h 39m
    $683–1,321

  8. Bus

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from Boston to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    40h
    $274–436

Lowell to Florida Keys by train, subway, bus, and foot

Calendar4Weekly Services
Duration38h 52mAverage Duration
Ticket$297Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lowell to Florida Keys.ExpandLaunch map view
  • Distance: 1,424.1 mi
  • Duration: 8h 57m

What companies run services between Lowell, MA, USA and Florida Keys, FL, USA?

American Airlines and JetBlue Airways fly from Boston Logan Airport (BOS) to Key West International Airport (EYW) 3 times a day. Alternatively, you can take a bus from Robert B Kennedy Bus Transfer Center to Florida Keys via Boston, Washington Union Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 40h.

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