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How to get fromLowell to Florida Keysby plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle

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There are 7 ways to get from Lowell to Florida Keys by plane, bus (Greyhound, Flixbus), train, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Key West International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Key West International Airport (EYW)plane plane BOS - EYW
    9h 4m
    $183–541

  2. Bus

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from Boston to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Miamibus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    40h 49m
    $272–497

  3. Train, bus

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Miami Amtrak Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    41h 23m
    $548–1,731

  4. Drive 1,628 mi

    1. Drive from Lowell to Florida Keyscar car 1,628 mi
    28h 33m
    $298–430

  5. Fly Boston Logan Airport to Miami International Airport, shuttle

    1. Fly from Boston Logan Airport (BOS) to Miami International Airport (MIA)plane plane BOS - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    11h 9m
    $343–1,051

  6. Fly Boston Logan Airport to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Boston Logan Airport (BOS) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane BOS - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    11h 35m
    $833–1,321

  7. Train, bus to Manchester Airport, fly to Key West International Airport

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Key West International Airport (EYW)plane plane MHT - EYW
    13h 3m
    $202–672

Lowell to Florida Keys by bus, taxi, and foot

Calendar4Weekly Services
Duration40h 49mAverage Duration
Ticket$272Cheapest Price
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Questions & Answers

Map of how to get from Lowell to Florida Keys.ExpandLaunch map view
  • Distance: 1,424.1 mi
  • Duration: 9h 4m

What companies run services between Lowell, MA, USA and Florida Keys, FL, USA?

American Airlines, JetBlue Airways, and Delta fly from Boston Logan Airport (BOS) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a bus from Robert B Kennedy Bus Transfer Center to Florida Keys via Boston, Washington Union Station, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 40h 49m.

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