There are 8 ways to get from Lowell to Greenville by plane, bus (Greyhound, Flixbus), train, bus, car, taxi, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Boston Logan Airport to Greenville–Spartanburg International Airport
best- Fly from Boston Logan Airport (BOS) to Greenville–Spartanburg International Airport (GSP)plane BOS - GSP
6h 36m$166–712Bus
- Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus
- Take the bus from Boston to NYC Downtownbus
- Take the bus from New York, NY to Gastonia, NC - Chester St.bus Nyc
- Take the bus from Los Arcos Restaurant - Gastonia to Taqueria Guadalajara - Greenvillebus
19h 38m$179–357Train, bus
- Take the train from Lowell to North Stationtrain
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus
23h 10m$304–1,325Drive 912 mi
- Drive from Lowell to Greenvillecar 912 mi
16h 52m$167–241Fly Boston Logan Airport to Asheville Regional Airport, taxi
- Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)plane BOS - AVL
- Take the taxi from Asheville-Airport-AVL to Greenvilletaxi
5h 36m$231–597Train, train to Theodore Francis Green State Airport, fly to Greenville–Spartanburg International Airport
- Take the train from Lowell to North Stationtrain
- Take the train from Ruggles to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Greenville–Spartanburg International Airport (GSP)plane PVD - GSP
7h 14m$312–973Train, bus to Manchester Airport, fly to Greenville–Spartanburg International Airport
- Take the train from Lowell to North Stationtrain
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Greenville–Spartanburg International Airport (GSP)plane MHT - GSP
8h 20m$430–973Bus via Atlanta
- Take the bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
32h 49m$232–506
Boston Logan Airport (BOS) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Lowell to Greenville is to drive which costs $160 - $240 and takes 16h 52m.
The fastest way to get from Lowell to Greenville is to fly and taxi which takes 5h 36m and costs $230 - $600.
No, there is no direct bus from Lowell to Greenville. However, there are services departing from Robert B Kennedy Bus Transfer Center and arriving at Taqueria Guadalajara - Greenville via Boston, New York, NY and Los Arcos Restaurant - Gastonia. The journey, including transfers, takes approximately 19h 38m.
The distance between Lowell and Greenville is 839 miles. The road distance is 917.3 miles.
The best way to get from Lowell to Greenville without a car is to bus which takes 19h 38m and costs $170 - $360.
It takes approximately 6h 36m to get from Lowell to Greenville, including transfers.
Lowell to Greenville bus services, operated by Greyhound USA, depart from Robert B Kennedy Bus Transfer Center station.
The best way to get from Lowell to Greenville is to fly which takes 6h 36m and costs $160 - $750. Alternatively, you can bus, which costs $170 - $360 and takes 19h 38m.
Lowell to Greenville bus services, operated by Greyhound USA, arrive at Boston station.
Yes, the driving distance between Lowell to Greenville is 917 miles. It takes approximately 16h 52m to drive from Lowell to Greenville.
What companies run services between Lowell, MA, USA and Greenville, SC, USA?
United Airlines, Southwest Airlines, and two other airlines fly from Boston Logan Airport (BOS) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Robert B Kennedy Bus Transfer Center to Greenville via Boston, NYC Downtown, New York, NY, Gastonia, NC - Chester St., Los Arcos Restaurant - Gastonia, and Taqueria Guadalajara - Greenville in around 19h 38m.
- Website
- aa.com
Flights from Boston Logan Airport to Greenville–Spartanburg International Airport via New York La Guardia
- Ave. Duration
- 4h 42m
- When
- Monday, Tuesday, Thursday, Friday, Wednesday, and Sunday
- Estimated price
- $120–650
Flights from Boston Logan Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $120–650
Flights from Boston Logan Airport to Greenville–Spartanburg International Airport via Philadelphia
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $120–650
Flights from Boston Logan Airport to Greenville–Spartanburg International Airport via Reagan Washington
- Ave. Duration
- 5h 53m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Boston Logan Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $85–420
Flights from Boston Logan Airport to Asheville Regional Airport via Philadelphia
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $80–410
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Reagan Washington
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $110–600
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Philadelphia
- Ave. Duration
- 4h 27m
- When
- Saturday
- Estimated price
- $110–600
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $140–750
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Philadelphia
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $140–700
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $210–950
- Website
- southwest.com
Flights from Boston Logan Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $120–650
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 6m
- When
- Monday to Saturday
- Estimated price
- $110–600
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 43m
- When
- Tuesday to Friday
- Estimated price
- $140–700
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $190–850
- Website
- delta.com
Flights from Boston Logan Airport to Greenville–Spartanburg International Airport via New York La Guardia
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 40m
- When
- Saturday and Sunday
- Estimated price
- $80–410
Flights from Boston Logan Airport to Asheville Regional Airport via New York La Guardia
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $80–410
Flights from Boston Logan Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $100–480
- Website
- united.com
Flights from Boston Logan Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $120–650
Flights from Boston Logan Airport to Asheville Regional Airport via Newark
- Ave. Duration
- 5h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–410
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $110–600
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $140–700
- Website
- allegiantair.com
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 21m
- When
- Monday and Friday
- Estimated price
- $80–410
- Website
- flybreeze.com
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 22m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $260–900
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $4–11
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $4–11
Train from Ruggles to TF Green Airport
- Ave. Duration
- 1h 22m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $9–15
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 57m
- Frequency
- Every 3 hours
- Estimated price
- $70–160
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Station
- Ave. Duration
- 12h 30m
- Frequency
- Twice daily
- Estimated price
- $190–400
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 44m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Robert B Kennedy Bus Transfer Center to Boston
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $4–8
- Website
- https://www.greyhound.com/
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- https://www.greyhound.com/
Bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminal
- Ave. Duration
- 7h 59m
- Frequency
- 5 times a week
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Port Authority Bus Terminal to Atlanta Bus Station
- Ave. Duration
- 18h 35m
- Frequency
- 4 times a day
- Estimated price
- $130–260
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Boston to NYC Downtown
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–60
- Schedules at
- flixbus.com
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from New York, NY to Gastonia, NC - Chester St.
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $90–130
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $90–130
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from Los Arcos Restaurant - Gastonia to Taqueria Guadalajara - Greenville
- Ave. Duration
- 1h 57m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Lowell to Greenville bus tickets online with Omio.
There are 272+ hotels available in Greenville.













