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How to get fromLowell to Louisvilleby plane, bus (Greyhound), train, bus, or car

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There are 9 ways to get from Lowell to Louisville by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Louisville International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane plane BOS - SDF
    6h 2m
    $152–770

  2. Train, train to Theodore Francis Green State Airport, fly to Louisville International Airport

    cheapest
    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Ruggles to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Louisville International Airport (SDF)plane plane PVD - SDF
    9h 40m
    $148–731

  3. Bus (Greyhound)

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from Boston to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Louisville Bus Stationbus bus
    26h
    $159–272

  4. Train, bus

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo Bus Stop to Louisville Bus Stationbus bus
    26h 2m
    $253–538

  5. Drive  939 mi

    1. Drive from Lowell to Louisvillecar car 939 mi
    16h 56m
    $172–248

  6. Fly Boston Logan Airport to Covington, bus

    1. Fly from Boston Logan Airport (BOS) to Covington (CVG)plane plane BOS - CVG
    2. Take the bus from Cincinnati to Louisvillebus bus
    8h 28m
    $442–1,064

  7. Train, bus to Manchester Airport, fly to Louisville International Airport

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Louisville International Airport (SDF)plane plane MHT - SDF
    9h 29m
    $227–1,129

  8. Train, bus via New York

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Cincinnatibus bus
    4. Take the bus from Cincinnati to Louisvillebus bus
    26h 31m
    $158–291

  9. Train, bus #2

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    32h 41m
    $320–1,358

Lowell to Louisville by bus (Greyhound)

Calendar5Weekly Buses
Duration26hAverage Duration
Ticket$159Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lowell to Louisville.ExpandLaunch map view
  • Distance: 861 mi
  • Duration: 6h 2m

What companies run services between Lowell, MA, USA and Louisville, KY, USA?

American Airlines, Delta, and two other airlines fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF) every 3 hours. Alternatively, you can take a bus from Robert B Kennedy Bus Transfer Center to Louisville Bus Station via Boston and Cleveland Bus Station in around 26h.

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