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How to get fromLowell to Louisvilleby plane, train, bus, car, or bus (Greyhound, Amtrak)

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There are 8 ways to get from Lowell to Louisville by plane, train, bus, car, or bus (Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Boston Logan Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane plane BOS - SDF
    6h 7m
    $172–870

  2. Train, bus to Manchester Airport, fly

    cheapest
    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Louisville International Airport (SDF)plane plane MHT - SDF
    9h 54m
    $158–780

  3. Train, bus

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    27h 13m
    $481–823

  4. Train, bus via New York

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Toledo Bus Stopbus bus
    4. Take the bus from Toledo to Indianapolisbus bus
    5. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    27h 15m
    $181–323

  5. Drive  939 mi

    1. Drive from Lowell to Louisvillecar car 939 mi
    16h 55m
    $172–248

  6. Train, train to Theodore Francis Green State Airport, fly

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Ruggles to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Louisville International Airport (SDF)plane plane PVD - SDF
    10h 1m
    $188–931

  7. Bus

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from Boston to New Yorkbus bus
    3. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    27h 17m
    $207–337

  8. Train, bus #2

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    32h 47m
    $580–1,608

Lowell to Louisville by train, subway, and bus

Calendar7Weekly Services
Duration27h 13mAverage Duration
Ticket$481Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lowell to Louisville.ExpandLaunch map view
  • Distance: 861 mi
  • Duration: 6h 7m

What companies run services between Lowell, MA, USA and Louisville, KY, USA?

American Airlines, Delta, and two other airlines fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from Robert B Kennedy Bus Transfer Center to Louisville, KY via Boston, New York, Port Authority Bus Terminal, and Indianapolis Union Station in around 27h 17m.

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