There are 6 ways to get from Lowell to Sanford by plane, train, bus (Greyhound, Flixbus), bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Boston Logan Airport, train
best- Fly from Boston Logan Airport (BOS) to Orlando (MCO)plane BOS - MCO
- Take the train from Sand Lake Road to Sanfordtrain
7h 32m$166–724Train, train to Theodore Francis Green State Airport, fly
cheapest- Take the train from Lowell to North Stationtrain
- Take the train from Ruggles to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Orlando (MCO)plane PVD - MCO
- Take the train from Sand Lake Road to Sanfordtrain
9h 35m$162–425Bus
- Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus
- Take the bus from Boston to Washington Union Stationbus
- Take the bus from Washington Union Station to Deltonabus
29h$217–384Bus, train
- Take the bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminalbus Greyhound US0256S
- Take the train from Ny Moynihan Train Hall At Penn Station to Delandtrain Silver Meteor
31h 47m$381–827Drive 1,262.9 mi
- Drive from Lowell to Sanfordcar 1,262.9 mi
21h 55m$231–333Train, bus to Manchester Airport, fly
- Take the train from Lowell to North Stationtrain
- Take the bus from Boston to Boston Manchester Airportbus
- Fly from Manchester Airport (MHT) to Orlando (MCO)plane MHT - MCO
- Take the train from Sand Lake Road to Sanfordtrain
9h 28m$220–635
Lowell to Sanford by bus, foot, and train
Questions & Answers
The cheapest way to get from Lowell to Sanford is to train and fly which costs $160 - $430 and takes 9h 35m.
The fastest way to get from Lowell to Sanford is to fly and train which takes 7h 32m and costs $160 - $750.
No, there is no direct bus from Lowell to Sanford. However, there are services departing from Robert B Kennedy Bus Transfer Center and arriving at Deltona via Boston and Washington Union Station. The journey, including transfers, takes approximately 29h.
The distance between Lowell and Sanford is 1191 miles. The road distance is 1270.3 miles.
The best way to get from Lowell to Sanford without a car is to bus which takes 29h and costs $210 - $390.
It takes approximately 7h 32m to get from Lowell to Sanford, including transfers.
Lowell to Sanford bus services, operated by Greyhound USA, depart from Robert B Kennedy Bus Transfer Center station.
Lowell to Sanford bus services, operated by Greyhound USA, arrive at Boston station.
Yes, the driving distance between Lowell to Sanford is 1270 miles. It takes approximately 21h 55m to drive from Lowell to Sanford.
There are 118+ hotels available in Sanford.
What companies run services between Lowell, MA, USA and Sanford, FL, USA?
You can take a bus from Robert B Kennedy Bus Transfer Center to Sanford via Boston, Washington Union Station, and Deltona in around 29h.
- Website
- southwest.com
Flights from Theodore Francis Green State Airport to Orlando
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- $90–450
Flights from Theodore Francis Green State Airport to Orlando via Baltimore
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $95–460
Flights from Manchester Airport to Orlando
- Ave. Duration
- 3h 12m
- When
- Every day
- Estimated price
- $120–600
Flights from Manchester Airport to Orlando via Baltimore
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $120–600
- Website
- jetblue.com
Flights from Boston Logan Airport to Orlando
- Ave. Duration
- 3h 14m
- When
- Every day
- Estimated price
- $100–490
Flights from Theodore Francis Green State Airport to Orlando
- Ave. Duration
- 2h 58m
- When
- Every day
- Estimated price
- $90–450
- Website
- united.com
Flights from Boston Logan Airport to Orlando via Washington Dulles
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $100–500
Flights from Manchester Airport to Orlando via Washington Dulles
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $120–600
- Website
- aa.com
Flights from Boston Logan Airport to Orlando
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- $100–490
Flights from Manchester Airport to Orlando via Charlotte
- Ave. Duration
- 5h 16m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–600
- Website
- delta.com
Flights from Boston Logan Airport to Orlando
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- $100–490
- Website
- flybreeze.com
Flights from Theodore Francis Green State Airport to Orlando
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- $140–390
Flights from Theodore Francis Green State Airport to Orlando via Wilmington
- Ave. Duration
- 5h 51m
- When
- Monday and Friday
- Estimated price
- $140–390
- Website
- flyfrontier.com
Flights from Boston Logan Airport to Orlando
- Ave. Duration
- 3h 34m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–430
- Phone
- +1 855-724-5411
- [email protected]
- Website
- SunRail
Train from Sand Lake Road to Sanford
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Train from Sand Lake Road to Sanford
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Train from Sand Lake Road to Sanford
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Deland
- Ave. Duration
- 21h 20m
- Frequency
- Once daily
- Estimated price
- $340–750
- Website
- Amtrak
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from Ruggles to TF Green Airport
- Ave. Duration
- 1h 17m
- Frequency
- Every 4 hours
- Estimated price
- $9–15
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–15
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Robert B Kennedy Bus Transfer Center to Boston
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $4–8
- Website
- Greyhound
Bus from Boston to Washington Union Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- Greyhound
Bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminal
- Ave. Duration
- 7h 59m
- Frequency
- 5 times a week
- Estimated price
- $35–75
- Website
- Greyhound
Bus from Boston to Boston Manchester Airport
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $7–15
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Washington Union Station
- Ave. Duration
- 9h 45m
- Frequency
- Twice daily
- Estimated price
- $75–130
- Schedules at
- Flixbus USA
Bus from Washington Union Station to Deltona
- Ave. Duration
- 16h 15m
- Frequency
- 4 times a week
- Estimated price
- $130–220
- Schedules at
- Flixbus USA
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