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How to get fromLowell to Winston-Salemby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 7 ways to get from Lowell to Winston-Salem by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Piedmont Triad International Airport (GSO)plane plane BOS - GSO
    7h 25m
    $160–790

  2. Bus via Boston

    cheapest
    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Winston-Salem, NCbus bus Nyc
    17h 50m
    $114–168

  3. Train, bus

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Lynchburgtrain train
    3. Take the train from Lynchburg to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    19h 16m
    $201–456

  4. Drive  743.1 mi

    1. Drive from Lowell to Winston-Salemcar car 743.1 mi
    14h 9m
    $136–196

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Boston Logan Airport (BOS) to Charlotte Douglas International Airport (CLT)plane plane BOS - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 49m
    $162–443

  6. Fly to Raleigh-Durham International Airport, bus

    1. Fly from Boston Logan Airport (BOS) to Raleigh-Durham International Airport (RDU)plane plane BOS - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    8h 32m
    $169–946

  7. Bus (Greyhound)

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Port Authority Bus Terminalbus bus Greyhound US0256S
    2. Take the bus from Port Authority Bus Terminal to Winston Salem(Trans Center)bus bus Greyhound US0670
    24h 14m
    $135–264

Lowell to Winston-Salem by train, subway, and bus

Calendar5Weekly Services
Duration19h 16mAverage Duration
Ticket$201Cheapest Price
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Questions & Answers

Map of how to get from Lowell to Winston-Salem.ExpandLaunch map view
  • Distance: 694.6 mi
  • Duration: 7h 25m

What companies run services between Lowell, MA, USA and Winston-Salem, NC, USA?

Delta, American Airlines, and United Airlines fly from Boston Logan Airport (BOS) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a bus from Robert B Kennedy Bus Transfer Center to Winston-Salem, NC via Boston, NYC Downtown, and New York, NY in around 17h 50m.

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