There are 7 ways to get from Lucca to Isernia by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Florence (Trenitalia)
best- Take the train from Lucca to Firenze S.M.N.train Re
- Take the train from Firenze S.M.N. to Roma Terminitrain Fr
- Take the train from Roma Termini to Iserniatrain Re
6h 12m€60–136Bus
cheapest- Take the bus from Lucca to Roma, Autostazione Tiburtinabus N503 / ...
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
7h 20m€36–66Drive 501.6 km
- Drive from Lucca to Iserniacar 501.6 km
4h 41m€78–113Bus, fly to Fiumicino International Airport, train
- Take the bus from Stazione fs Lucca to Firenze T2 Guidonibus
- Fly from Florence Peretola Airport (FLR) to Fiumicino International Airport (FCO)plane FLR - FCO
- Take the train from Roma Termini to Iserniatrain
6h 41m€92–243Train (Trenitalia)
- Take the train from Pisa Centrale to Roma Terminitrain Fb / ...
- Take the train from Roma Termini to Iserniatrain Re
6h 55m€61–145Bus, train
- Take the bus from Lucca to Cassinobus
- Take the train from Cassino to Iserniatrain Re
8h 36m€36–53Bus, fly to Naples Airport, train
- Take the bus from Stazione fs Lucca to Firenze T2 Guidonibus
- Fly from Florence Peretola Airport (FLR) to Naples Airport (NAP)plane FLR - NAP
- Take the train from Caserta to Iserniatrain
8h 44m€98–259
Lucca to Isernia by train (Trenitalia)
Questions & Answers
The cheapest way to get from Lucca to Isernia is to bus and train which costs €35 - €55 and takes 8h 36m.
The fastest way to get from Lucca to Isernia is to drive which takes 4h 41m and costs €75 - €120.
No, there is no direct bus from Lucca to Isernia. However, there are services departing from Lucca and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 7h 20m.
No, there is no direct train from Lucca to Isernia. However, there are services departing from Lucca and arriving at Isernia via Firenze S.M.N. and Roma Termini. The journey, including transfers, takes approximately 6h 12m.
The distance between Lucca and Isernia is 524 km. The road distance is 501.6 km.
The best way to get from Lucca to Isernia without a car is to train via Florence which takes 6h 12m and costs €55 - €140.
It takes approximately 6h 12m to get from Lucca to Isernia, including transfers.
Lucca to Isernia bus services, operated by FlixBus, depart from Lucca station.
Lucca to Isernia train services, operated by Trenitalia, depart from Lucca station.
The best way to get from Lucca to Isernia is to train via Florence which takes 6h 12m and costs €55 - €140. Alternatively, you can bus, which costs €35 - €70 and takes 7h 20m.
What companies run services between Lucca, Italy and Isernia, Italy?
You can take a train from Lucca to Isernia via Firenze S.M.N. and Roma Termini in around 6h 12m. Alternatively, you can take a bus from Lucca to Isernia via Roma, Autostazione Tiburtina in around 7h 20m.
- Website
- ita-airways.com
Flights from Florence Peretola Airport to Fiumicino International Airport
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- €60–180
Flights from Florence Peretola Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- €130–200
- Website
- easyjet.com
Flights from Florence Peretola Airport to Naples Airport via Nice
- Ave. Duration
- 3h 45m
- When
- Monday and Wednesday
- Estimated price
- €85–250
Flights from Florence Peretola Airport to Naples Airport via Olbia
- Ave. Duration
- 3h 50m
- When
- Wednesday
- Estimated price
- €85–250
Flights from Florence Peretola Airport to Naples Airport via Palermo
- Ave. Duration
- 4h 40m
- When
- Monday, Wednesday, and Friday
- Estimated price
- €60–230
- Website
- ryanair.com
Flights from Florence Peretola Airport to Naples Airport via Catania
- Ave. Duration
- 4h
- When
- Monday, Friday, and Sunday
- Estimated price
- €90–220
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lucca to Firenze S.M.N.
- Ave. Duration
- 1h 21m
- Frequency
- Every 30 minutes
- Estimated price
- €9–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 3h 51m
- Frequency
- Every 4 hours
- Estimated price
- €30–55
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Pisa Centrale to Roma Termini
- Ave. Duration
- 4h 10m
- Frequency
- Hourly
- Estimated price
- €40–70
- Website
- Trenitalia
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Every 3 hours
- Estimated price
- €23–40
- Website
- Trenitalia
Train from Cassino to Isernia
- Ave. Duration
- 40 min
- Frequency
- Every 3 hours
- Estimated price
- €6–11
- Website
- Trenitalia
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- Every 3 hours
- Estimated price
- €11–19
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 1h 36m
- Frequency
- Every 15 minutes
- Estimated price
- €35–80
- Schedules at
- Trenitalia Frecce
Train from Pisa Centrale to Roma Termini
- Ave. Duration
- 2h 56m
- Frequency
- Hourly
- Estimated price
- €45–100
- Schedules at
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Roma Termini
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €27–60
- Website
- Trenitalia Intercity
Train from Pisa Centrale to Roma Termini
- Ave. Duration
- 3h 22m
- Frequency
- Every 4 hours
- Estimated price
- €35–75
- Website
- Trenitalia Intercity
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Lucca to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h 10m
- Frequency
- Twice daily
- Estimated price
- €27–45
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €13–22
- Website
- Flixbus
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
- Phone
- +39 800 142 424
- [email protected]
- Website
- Autolinee Toscane
Bus from Stazione fs Lucca to Firenze T2 Guidoni
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- €4–6
- Website
- Autolinee Toscane
- Schedules at
- Autolinee Toscane
Bus from Stazione fs Lucca to Firenze T2 Guidoni
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- €4–6
- Website
- Autolinee Toscane
- Schedules at
- Autolinee Toscane
- Phone
- +39 089 233 899
- [email protected]
- Website
- Curcio Viaggi
Bus from Lucca to Cassino
- Ave. Duration
- 6h 50m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- Curcio Viaggi
Want to know more about travelling around Italy
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More Questions & Answers
Lucca to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Lucca to Isernia train services, operated by Trenitalia, arrive at Firenze S.M.N. station.
Yes, the driving distance between Lucca to Isernia is 502 km. It takes approximately 4h 41m to drive from Lucca to Isernia.
Book your Lucca to Isernia train tickets online with Omio.
Book your Lucca to Isernia bus tickets online with Omio and FlixBus.
There are 482+ hotels available in Isernia.



























