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How to get fromLugano to Mainzby train (Trenitalia), bus, night train, train, car, or plane

Find Transport to Mainz

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There are 8 ways to get from Lugano to Mainz by train (Trenitalia), bus, night train, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Basel

    best
    1. Take the train from Lugano to Basel SBBtrain train Ec
    2. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    7h 5m
    €72–311

  2. Train to Milan Linate Airport, fly

    cheapest
    1. Take the train from Lugano to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    5h 44m
    €46–182

  3. Bus

    1. Take the bus from Lugano to Frankfurt central train stationbus bus FlixBus N474
    10h 50m
    €60–88

  4. Bus, night train, train

    1. Take the bus from Lugano Via Giacomo and Filippo Ciani to Zurich Central Bus Station Sihlquaibus bus
    2. Take the nighttrain from Zuerich Hb to Mannheim Hbfnighttrain night train Nj
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    11h 52m
    €53–172

  5. Drive  587.3 km

    1. Drive from Lugano to Mainzcar car 587.3 km
    5h 24m
    €106–154

  6. Train

    1. Take the train from Lugano to Mannheim Hbftrain train Ec
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    7h 6m
    €121–216

  7. Train to Zurich Airport, fly

    1. Take the train from Lugano to Zürich HBtrain train
    2. Fly from Zurich Airport (ZRH) to Frankfurt (FRA)plane plane ZRH - FRA
    4h 36m
    €173–352

  8. Train to Milano Malpensa Airport, fly

    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    5h 19m
    €65–208

Lugano to Mainz by train

Calendar86Weekly Trains
Duration7h 5mAverage Duration
Ticket€72Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lugano to Mainz.ExpandLaunch map view
  • Distance: 575.5 km
  • Duration: 7h 5m

What companies run services between Lugano, Switzerland and Mainz, Germany?

You can take a train from Lugano to Mainz, Hauptbahnhof via Basel SBB and Mannheim, Hauptbahnhof in around 7h 5m. Alternatively, FlixBus operates a bus from Lugano to Frankfurt central train station 5 times a week. Tickets cost €55–85 and the journey takes 9h 5m.

Airlines
Train operators
Bus operators

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