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How to get fromLugano to Mainzby train (Trenitalia), bus, car, train, or plane

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There are 9 ways to get from Lugano to Mainz by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Basel

    best
    1. Take the train from Lugano to Basel SBBtrain train Ec
    2. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train 55 / ...
    6h 19m
    €77–535

  2. Train to Milan Linate Airport, fly

    cheapest
    1. Take the train from Lugano to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Frankfurt (FRA)plane plane LIN - FRA
    5h 49m
    €48–154

  3. Bus

    1. Take the bus from Lugano to Frankfurt central train stationbus bus FlixBus N474
    10h 50m
    €52–85

  4. Drive 587.3 km

    1. Drive from Lugano to Mainzcar car 587.3 km
    5h 24m
    €102–148

  5. Train to Milano Malpensa Airport, fly

    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Frankfurt (FRA)plane plane MXP - FRA
    5h 18m
    €67–200

  6. Train

    1. Take the train from Lugano to Mannheim Hbftrain train Ec
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    7h 8m
    €123–190

  7. Bus, train

    1. Take the bus from Lugano to Basel, Meret Oppenheim-Strasse (Bahnhof SBB)bus bus BlaBlaCar Bus
    2. Take the train from Basel SBB to Mainz, Hauptbahnhoftrain train 43N
    9h 21m
    €90–344

  8. Train to Zurich Airport, fly

    1. Take the train from Lugano to Zürich HBtrain train
    2. Fly from Zurich Airport (ZRH) to Frankfurt (FRA)plane plane ZRH - FRA
    5h 40m
    €152–400

  9. Train to Basel, fly

    1. Take the train from Lugano to Basel SBBtrain train
    2. Fly from Basel (BSL) to Frankfurt (FRA)plane plane BSL - FRA
    6h 49m
    €127–569

Lugano to Mainz by train

Calendar88Weekly Trains
Duration6h 19mAverage Duration
Ticket€77Cheapest Price
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Questions & Answers

Map of how to get from Lugano to Mainz.ExpandLaunch map view
  • Distance: 575.5 km
  • Duration: 6h 19m

What companies run services between Lugano, Switzerland and Mainz, Germany?

You can take a train from Lugano to Mainz, Hauptbahnhof via Basel SBB and Mannheim, Hauptbahnhof in around 6h 19m. Alternatively, FlixBus operates a bus from Lugano to Frankfurt central train station once daily. Tickets cost €45–80 and the journey takes 9h 5m.

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