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How to get fromLugano to Sienaby bus, train (Trenitalia), car, train, or plane

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There are 7 ways to get from Lugano to Siena by bus, train (Trenitalia), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Lugano Via Pian Scairolo to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    5h 7m

  2. Bus via Lugano Via Giacomo and Filippo Ciani

    cheapest
    1. Take the bus from Lugano Via Giacomo and Filippo Ciani to Florence - Villa Costanzabus bus 36
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    9h 8m
    €30–57

  3. Train

    1. Take the train from Lugano to Milano Centraletrain train
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    5h 24m
    €69–193

  4. Drive 438.6 km

    1. Drive from Lugano to Sienacar car 438.6 km
    4h 31m
    €77–111

  5. Train to Milano Malpensa Airport, fly, train

    1. Take the train from Lugano to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane plane MXP - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 32m
    €104–218

  6. Train to Milan Linate Airport, fly, train

    1. Take the train from Lugano to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Florence Peretola Airport (FLR)plane plane LIN - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 42m
    €130–302

  7. Train to Zurich Airport, fly, train

    1. Take the train from Lugano to Zuerich Hbtrain train
    2. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 47m
    €159–360

Lugano to Siena by train

Calendar114Weekly Trains
Duration5h 24mAverage Duration
Ticket€69Cheapest Price
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Questions & Answers

Map of how to get from Lugano to Siena.ExpandLaunch map view
  • Distance: 462.5 km
  • Duration: 5h 7m

What companies run services between Lugano, Switzerland and Siena, Italy?

You can take a bus from Lugano Via Pian Scairolo to Siena via Florence Villa Constanza Bus Station in around 5h 7m. Alternatively, you can take a train from Lugano to Siena via Milano Centrale and Firenze S.M.N. in around 5h 24m.

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