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How to get fromLuxembourg to Iserniaby plane, train, bus, train (Eurostar, Trenitalia), or car

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There are 7 ways to get from Luxembourg to Isernia by plane, train, bus, train (Eurostar, Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Naples Airport, train

    best
    1. Fly from Luxembourg (LUX) to Naples Airport (NAP)plane plane LUX - NAP
    2. Take the train from Caserta to Iserniatrain train
    7h 55m
    €68–263
  2. Fly to Abruzzo Airport, train, bus

    cheapest
    1. Fly from Luxembourg (LUX) to Abruzzo Airport (PSR)plane plane LUX - PSR
    2. Take the train from Pescara Porta Nuova to Montenero-Petacciatotrain train
    3. Take the bus from Montenero Bivio SS16 to Iserniabus bus
    9h 26m
    €65–326
  3. Bus

    1. Take the bus from Luxembourg Park&Drive to Casello - A1 Ingresso Caianellobus bus
    2. Take the bus from Casello - A1 Ingresso Caianello to Iserniabus bus 6
    19h 42m
  4. Train

    1. Take the train from Luxembourg to Bruxelles-Miditrain train Ic / ...
    2. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    3. Take the train from Chambery Challes Les Eaux to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Roma Terminitrain train
    5. Take the train from Roma Termini to Iserniatrain train Re
    19h 43m
    €421–766
  5. Drive 1,379.9 km

    1. Drive from Luxembourg to Iserniacar car 1,379.9 km
    13h 44m
    €217–313
  6. Fly to Fiumicino International Airport, train

    1. Fly from Luxembourg (LUX) to Fiumicino International Airport (FCO)plane plane LUX - FCO
    2. Take the train from Roma Termini to Iserniatrain train
    8h 1m
    €91–287
  7. Bus via Karlsruhe

    1. Take the bus from Luxembourg, P+R Bouillon to Karlsruhe central train stationbus bus
    2. Take the bus from Karlsruhe central train station to Pescarabus bus
    3. Take the bus from Pescara to Iserniabus bus
    25h 25m
    €134–238

Luxembourg to Isernia by train

Calendar5Weekly Trains
Duration19h 43mAverage Duration
Ticket€421Cheapest Price
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Questions & Answers

What companies run services between Luxembourg and Isernia, Italy?

You can take a bus from Luxembourg Park&Drive to Isernia via Casello - A1 Ingresso Caianello in around 19h 42m. Alternatively, you can take a train from Luxembourg to Isernia via Brussel-Zuid / Bruxelles-Midi, Chambery Challes Les Eaux, Milano Centrale, and Roma Termini in around 19h 43m.

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