There are 7 ways to get from Luxembourg to Palermo by plane, bus, train, train (Eurostar, Trenitalia), car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Luxembourg
best- Fly from Luxembourg (LUX) to Palermo Airport (PMO)plane LUX - PMO
5h 34m€53–295Bus, train
- Take the bus from Luxembourg Park&Drive to Salernobus
- Take the train from Salerno to Palermo Centraletrain Ic
28h 48m€234–349Train
- Take the train from Luxembourg to Bruxelles-Miditrain Ic / ...
- Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
28h 59m€537–908Drive, car ferry
- Drive from Luxembourg to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
29h 17m€229–336Bus to Brussels South Charleroi Airport, fly
- Take the bus from Luxembourg P+R Bouillon to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Palermo Airport (PMO)plane CRL - PMO
7h 42m€73–296Bus
- Take the bus from Luxembourg Park&Drive to Palermo Piazza Cairolibus
33h 47m€290–400Bus via Aosta
- Take the bus from Luxembourg, P+R Bouillon to Aostabus FlixBus N506
- Take the bus from Aosta to Palermobus N597
36h 10m€218–325
Luxembourg to Palermo by bus
Comparing Your Travel Options
The cheapest way to get from Luxembourg to Palermo is to fly which costs €50 - €300 and takes 5h 34m.
The fastest way to get from Luxembourg to Palermo is to fly which takes 5h 34m and costs €50 - €300.
Yes, there is a direct bus departing from Luxembourg Park&Drive and arriving at Palermo Piazza Cairoli. Services depart once a week. The journey takes approximately 33h 47m.
No, there is no direct train from Luxembourg to Palermo. However, there are services departing from Luxembourg and arriving at Palermo Centrale via Brussel-Zuid / Bruxelles-Midi, Chambery Challes Les Eaux, Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 28h 59m.
The distance between Luxembourg and Palermo is 1424 km.
The best way to get from Luxembourg to Palermo without a car is to bus and train which takes 28h 48m and costs €230 - €350.
It takes approximately 5h 34m to get from Luxembourg to Palermo, including transfers.
Luxembourg to Palermo bus services, operated by Onebus, depart from Luxembourg Park&Drive station.
Luxembourg to Palermo train services, operated by Belgian Railways (NMBS/SNCB), depart from Luxembourg station.
The best way to get from Luxembourg to Palermo is to fly which takes 5h 34m and costs €50 - €300. Alternatively, you can train, which costs €500 - €950 and takes 28h 59m, you could also bus, which costs €290 - €400 and takes 33h 47m.
What companies run services between Luxembourg and Palermo, Italy?
Luxair, Ryanair, and ITA Airways fly from Luxembourg (LUX) to Palermo Airport (PMO) twice daily. Alternatively, you can take a train from Luxembourg to Palermo Centrale via Brussel-Zuid / Bruxelles-Midi, Chambery Challes Les Eaux, Milano Centrale, and Roma Termini in around 28h 59m.
- Website
- ryanair.com
Flights from Luxembourg to Palermo Airport via Milan Bergamo
- Ave. Duration
- 4h 15m
- When
- Saturday, Thursday, and Sunday
- Estimated price
- €50–210
Flights from Brussels South Charleroi Airport to Palermo Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €40–220
Flights from Brussels South Charleroi Airport to Palermo Airport via Turin
- Ave. Duration
- 4h 10m
- When
- Thursday, Tuesday, and Friday
- Estimated price
- €40–220
Flights from Brussels South Charleroi Airport to Palermo Airport via Pisa
- Ave. Duration
- 4h 35m
- When
- Friday and Sunday
- Estimated price
- €40–220
Flights from Brussels South Charleroi Airport to Palermo Airport via Milan Bergamo
- Ave. Duration
- 5h 18m
- When
- Saturday and Friday
- Estimated price
- €40–220
Flights from Brussels South Charleroi Airport to Palermo Airport via Verona
- Ave. Duration
- 4h 50m
- When
- Sunday
- Estimated price
- €40–220
- Website
- luxair.lu
Flights from Luxembourg to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Thursday and Sunday
- Estimated price
- €90–360
Flights from Luxembourg to Palermo Airport via Rome
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- €90–370
- Website
- ita-airways.com
Flights from Luxembourg to Palermo Airport via Milan Linate
- Ave. Duration
- 4h 45m
- When
- Sunday
- Estimated price
- €140–550
Flights from Luxembourg to Palermo Airport via Rome
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- €90–370
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Salerno to Palermo Centrale
- Ave. Duration
- 8h 32m
- Frequency
- Twice daily
- Estimated price
- €65–120
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Luxembourg to Bruxelles-Midi
- Ave. Duration
- 3h 17m
- Frequency
- Hourly
- Estimated price
- €40–65
- Website
- Belgian Railways
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eaux
- Ave. Duration
- 4h 29m
- Frequency
- Twice a week
- Estimated price
- €300–500
- Website
- Eurostar
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Chambery Challes Les Eaux to Milano Centrale
- Ave. Duration
- 3h 21m
- Frequency
- Twice daily
- Estimated price
- €40–55
- Website
- Trenitalia
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–120
- Website
- Italo Treno
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Luxembourg Park&Drive to Salerno
- Ave. Duration
- 18h 38m
- Frequency
- Once a week
- Estimated price
- €160–230
- Website
- Onebus
Bus from Luxembourg Park&Drive to Palermo Piazza Cairoli
- Ave. Duration
- 33h 47m
- Frequency
- Once a week
- Estimated price
- €290–400
- Website
- Onebus
- Phone
- +352 50 55 62 63 10
- [email protected]
- Website
- Flibco
Bus from Luxembourg P+R Bouillon to Charleroi Airport
- Ave. Duration
- 2h 10m
- Frequency
- Every 3 hours
- Estimated price
- €19–55
- Website
- Flibco
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Luxembourg, P+R Bouillon to Aosta
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- €55–85
- Website
- Flixbus
Bus from Aosta to Palermo
- Ave. Duration
- 25h 45m
- Frequency
- Once daily
- Estimated price
- €160–240
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
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Booking & Getting There
Luxembourg to Palermo bus services, operated by Onebus, arrive at Palermo Piazza Cairoli station.
Luxembourg to Palermo train services, operated by Belgian Railways (NMBS/SNCB), arrive at Bruxelles-Midi station.
Book your Luxembourg to Palermo train tickets online with Omio.
Book your Luxembourg to Palermo bus tickets online with Omio.
There are 6143+ hotels available in Palermo.






































