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How to get fromLuxembourg to Sienaby plane, train, bus, train (Eurostar, TGV, Trenitalia), or car

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There are 9 ways to get from Luxembourg to Siena by plane, train, bus, train (Eurostar, TGV, Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Luxembourg to Florence Peretola Airport, train

    best
    1. Fly from Luxembourg (LUX) to Florence Peretola Airport (FLR)plane plane LUX - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 30m
    €113–348

  2. Bus to Brussels South Charleroi Airport, fly to Pisa International Airport, train

    cheapest
    1. Take the bus from Luxembourg P+R Bouillon to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane plane CRL - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    8h 5m
    €87–267

  3. Bus, train

    1. Take the bus from Luxembourg, Gare Centrale routière to Louvignybus bus L95
    2. Take the train from Lorraine Tgv to Strasbourgtrain train Tgv
    3. Take the train from Strasbourg to Basel Sbbtrain train Ter
    4. Take the bus from Basel to Florence Villa Constanza Bus Stationbus bus
    5. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    13h 3m

  4. Train

    1. Take the train from Luxembourg to Bruxelles-Miditrain train Ic / ...
    2. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    3. Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain train Tgv
    4. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    17h 47m
    €457–800

  5. Drive  1,020.1 km

    1. Drive from Luxembourg to Sienacar car 1,020.1 km
    10h 35m
    €185–267

  6. Train to Brussels Airport, fly to Florence Peretola Airport, train

    1. Take the train from Luxembourg to Bruxelles-Schumantrain train
    2. Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane plane BRU - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    9h 37m
    €126–294

  7. Fly Luxembourg to Milan Linate Airport, train

    1. Fly from Luxembourg (LUX) to Milan Linate Airport (LIN)plane plane LUX - LIN
    2. Take the train from Milano Rogoredo to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 8m
    €88–381

  8. Bus

    1. Take the bus from Luxembourg Park&Drive to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 1518 / ...
    15h 57m
    €144–196

  9. Bus via Milan

    1. Take the bus from Luxembourg to Milano, Autostazione Lampugnanobus bus BlaBlaCar Bus
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    16h 40m
    €88–145

Luxembourg to Siena by train

Calendar5Weekly Trains
Duration17h 47mAverage Duration
Ticket€457Cheapest Price
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Comparing Your Travel Options

Map of how to get from Luxembourg to Siena.ExpandLaunch map view
  • Distance: 856.8 km
  • Duration: 6h 30m

What companies run services between Luxembourg and Siena, Italy?

You can take a train from Luxembourg to Siena via Brussel-Zuid / Bruxelles-Midi, Chambery Challes Les Eaux, Torino Porta Susa, and Firenze S.M.N. in around 17h 47m. Alternatively, you can take a bus from Luxembourg Park&Drive to Siena via Florence Villa Constanza Bus Station in around 15h 57m.

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