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How to get fromLuxembourg to Sienaby plane, train, bus, train (Eurostar, Trenitalia), or car

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There are 8 ways to get from Luxembourg to Siena by plane, train, bus, train (Eurostar, Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Luxembourg to Florence Peretola Airport, train

    best
    1. Fly from Luxembourg (LUX) to Florence Peretola Airport (FLR)plane plane LUX - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 50m
    €113–320

  2. Bus via Milan

    cheapest
    1. Take the bus from Luxembourg to Milano, Autostazione Lampugnanobus bus BlaBlaCar Bus
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    15h 55m
    €84–141

  3. Train, bus

    1. Take the train from Thionville to Strasbourgtrain train Tgv
    2. Take the train from Strasbourg to Basel Sbbtrain train Ter
    3. Take the bus from Basel to Florence Villa Constanza Bus Stationbus bus
    4. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    13h 51m
    €143–230

  4. Train

    1. Take the train from Luxembourg to Bruxelles-Miditrain train Ic / ...
    2. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    3. Take the train from Chambery Challes Les Eaux to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    17h 59m
    €354–644

  5. Drive  1,017.6 km

    1. Drive from Luxembourg to Sienacar car 1,017.6 km
    10h 38m
    €162–234

  6. Fly Luxembourg to Bologna Guglielmo Marconi Airport, train

    1. Fly from Luxembourg (LUX) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LUX - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 22m
    €95–313

  7. Bus to Brussels South Charleroi Airport, fly to Pisa International Airport, train

    1. Take the bus from Luxembourg P+R Bouillon to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane plane CRL - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    8h 31m
    €92–331

  8. Bus

    1. Take the bus from Luxembourg Park&Drive to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    16h 10m
    €145–195

Luxembourg to Siena by train

Calendar2Weekly Trains
Duration17h 59mAverage Duration
Ticket€354Cheapest Price
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Questions & Answers

Map of how to get from Luxembourg to Siena.ExpandLaunch map view
  • Distance: 856.8 km
  • Duration: 6h 50m

What companies run services between Luxembourg and Siena, Italy?

You can take a train from Luxembourg to Siena via Brussel-Zuid / Bruxelles-Midi, Chambery Challes Les Eaux, Milano Centrale, and Firenze S.M.N. in around 17h 59m. Alternatively, you can take a bus from Luxembourg to Siena via Milano, Autostazione Lampugnano in around 15h 55m.

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