Rome2Rio

How to get fromLuxembourg to Sienaby plane, train, bus, train (Eurostar, Trenitalia), or car

Find Transport to Siena

See all options

There are 9 ways to get from Luxembourg to Siena by plane, train, bus, train (Eurostar, Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Luxembourg to Florence Peretola Airport, train

    best
    1. Fly from Luxembourg (LUX) to Florence Peretola Airport (FLR)plane plane LUX - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 55m
    €113–338

  2. Bus via Milan

    cheapest
    1. Take the bus from Luxembourg to Milano, Autostazione Lampugnanobus bus BlaBlaCar Bus
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    16h 40m
    €84–137

  3. Train, bus

    1. Take the train from Thionville to Strasbourgtrain train Tgv
    2. Take the train from Strasbourg to Basel Sbbtrain train Ter
    3. Take the bus from Basel to Florence Villa Constanza Bus Stationbus bus
    4. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    13h 51m
    €147–229

  4. Train

    1. Take the train from Luxembourg to Bruxelles-Miditrain train Ic / ...
    2. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    3. Take the train from Chambery Challes Les Eaux to Milano Centraletrain train Fr
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    18h 4m
    €423–708

  5. Drive  1,017.6 km

    1. Drive from Luxembourg to Sienacar car 1,017.6 km
    10h 39m
    €165–238

  6. Fly Luxembourg to Bologna Guglielmo Marconi Airport, train

    1. Fly from Luxembourg (LUX) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LUX - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    7h 23m
    €100–308

  7. Bus to Brussels South Charleroi Airport, fly to Pisa International Airport, train

    1. Take the bus from Luxembourg P+R Bouillon to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane plane CRL - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    8h 26m
    €87–287

  8. Train to Brussels Airport, fly to Florence Peretola Airport, train

    1. Take the train from Luxembourg to Bruxelles-Schumantrain train
    2. Fly from Brussels Airport (BRU) to Florence Peretola Airport (FLR)plane plane BRU - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    10h 2m
    €121–302

  9. Bus

    1. Take the bus from Luxembourg Park&Drive to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 1518 / ...
    15h 57m
    €143–196

Luxembourg to Siena by train

Calendar2Weekly Trains
Duration18h 4mAverage Duration
Ticket€423Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Luxembourg to Siena.ExpandLaunch map view
  • Distance: 856.8 km
  • Duration: 6h 55m

What companies run services between Luxembourg and Siena, Italy?

You can take a train from Luxembourg to Siena via Brussel-Zuid / Bruxelles-Midi, Chambery Challes Les Eaux, Milano Centrale, and Firenze S.M.N. in around 18h 4m. Alternatively, you can take a bus from Luxembourg Park&Drive to Siena via Florence Villa Constanza Bus Station in around 15h 57m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

Booking & Getting There