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How to get fromLuxembourg to Sienaby plane, train, bus, train (Eurostar, TGV, Trenitalia), or car

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There are 8 ways to get from Luxembourg to Siena by plane, train, bus, train (Eurostar, TGV, Trenitalia), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Luxembourg to Florence Peretola Airport, train

    best
    1. Fly from Luxembourg (LUX) to Florence Peretola Airport (FLR)plane plane LUX - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 35m
    €113–311

  2. Fly Luxembourg to Bologna Guglielmo Marconi Airport, train

    cheapest
    1. Fly from Luxembourg (LUX) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LUX - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 50m
    €90–306

  3. Bus

    1. Take the bus from Luxembourg to Milano, Autostazione Lampugnanobus bus BlaBlaCar Bus
    2. Take the bus from Milano, Autostazione Lampugnano to Sienabus bus N528 / ...
    15h 55m
    €92–163

  4. Train

    1. Take the train from Luxembourg to Bruxelles-Miditrain train Ic / ...
    2. Take the train from Brussel-Zuid / Bruxelles-Midi to Chambery Challes Les Eauxtrain train
    3. Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain train Tgv
    4. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    17h 48m
    €369–720

  5. Drive 1,017.6 km

    1. Drive from Luxembourg to Sienacar car 1,017.6 km
    10h 38m
    €160–231

  6. Bus to Brussels South Charleroi Airport, fly to Pisa International Airport, train

    1. Take the bus from Luxembourg P+R Bouillon to Charleroi Airportbus bus
    2. Fly from Brussels South Charleroi Airport (CRL) to Pisa International Airport (PSA)plane plane CRL - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    8h 10m
    €92–287

  7. Fly Luxembourg to Milan Linate Airport, train

    1. Fly from Luxembourg (LUX) to Milan Linate Airport (LIN)plane plane LUX - LIN
    2. Take the train from Milano Rogoredo to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 5m
    €98–364

  8. Bus, train

    1. Take the bus from Luxembourg Park&Drive to Florence Villa Constanza Bus Stationbus bus
    2. Take the train from Firenze S.M.N. to Sienatrain train Re
    16h 36m

Luxembourg to Siena by bus

Calendar14Weekly Buses
Duration15h 55mAverage Duration
Ticket€92Cheapest Price
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Questions & Answers

Map of how to get from Luxembourg to Siena.ExpandLaunch map view
  • Distance: 856.8 km
  • Duration: 6h 35m

What companies run services between Luxembourg and Siena, Italy?

You can take a bus from Luxembourg to Siena via Milano, Autostazione Lampugnano in around 15h 55m. Alternatively, you can take a train from Luxembourg to Siena via Brussel-Zuid / Bruxelles-Midi, Chambery Challes Les Eaux, Torino Porta Susa, and Firenze S.M.N. in around 17h 48m.

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