There are 10 ways to get from Lyon to Brussels Central Station by train (TGV), bus, rideshare, plane, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (TGV)
best- Take the train from Lyon Part Dieu to Brussel-Zuid / Bruxelles-Miditrain Tgv
3h 56m€160–249Rideshare
cheapest- Take the rideshare from Lyon to Brussels662.8 km
8h 36m€47–48Bus
- Take the bus from Lyon to Brussels-North train stationbus N845
10h 25m€58–94Fly Lyon–Saint Exupéry Airport to Brussels Airport
- Fly from Lyon–Saint Exupéry Airport (LYS) to Brussels Airport (BRU)plane LYS - BRU
4h 22m€102–241Train via Lyon Perrache (TGV)
- Take the train from Lyon Perrache to Brussel-Zuid / Bruxelles-Miditrain Tgv
4h 40m€160–250Train, bus
- Take the train from Lyon Part Dieu to Chalon Sur Saonetrain Ter / ...
- Take the bus from Chalon-sur-Saône - Train Station to Brussels - Midi Train Stationbus BlaBlaCar Bus
10h 29m€73–137Drive 663.5 km
- Drive from Lyon to Brussels Central Stationcar 663.5 km
7h 24m€104–149Train to Geneva International Airport, fly to Brussels Airport
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Brussels Airport (BRU)plane GVA - BRU
6h 7m€86–256Fly Lyon–Saint Exupéry Airport to Paris Charles De Gaulle Airport, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Paris Charles De Gaulle Airport (CDG)plane LYS - CDG
- Take the train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Miditrain
5h 2m€182–457Fly Lyon–Saint Exupéry Airport to Amsterdam Airport Schiphol, train
- Fly from Lyon–Saint Exupéry Airport (LYS) to Amsterdam Airport Schiphol (AMS)plane LYS - AMS
- Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain
6h 23m€187–397
Lyon to Brussels Central Station by train (TGV)
Questions & Answers
The cheapest way to get from Lyon to Brussels Central Station is to rideshare which costs €47 - €48 and takes 8h 36m.
The fastest way to get from Lyon to Brussels Central Station is to train which takes 3h 56m and costs €160 - €250.
No, there is no direct bus from Lyon to Brussels Central Station station. However, there are services departing from Lyon and arriving at Brussels-North train station via . The journey, including transfers, takes approximately 10h 25m.
Yes, there is a direct train departing from Lyon Perrache and arriving at Brussel-Zuid / Bruxelles-Midi. Services depart twice daily, and operate Monday to Saturday. The journey takes approximately 4h 16m.
The distance between Lyon and Brussels Central Station is 752 km. The road distance is 663.5 km.
The best way to get from Lyon to Brussels Central Station without a car is to train which takes 3h 56m and costs €160 - €250.
It takes approximately 3h 56m to get from Lyon to Brussels Central Station, including transfers.
Lyon to Brussels Central Station bus services, operated by FlixBus, depart from Lyon station.
Lyon to Brussels Central Station train services, operated by TGV inOui, depart from Lyon Part Dieu station.
The best way to get from Lyon to Brussels Central Station is to train which takes 3h 56m and costs €160 - €250. Alternatively, you can bus, which costs €55 - €95 and takes 10h 25m, you could also fly, which costs €100 - €250 and takes 4h 22m.
What companies run services between Lyon, France and Brussels Central Station, Belgium?
TGV inOui operates a train from Lyon Part Dieu to Brussel-Zuid / Bruxelles-Midi hourly. Tickets cost €150–250 and the journey takes 3h 51m. Alternatively, FlixBus operates a bus from Lyon to Brussels-North train station 5 times a week. Tickets cost €55–95 and the journey takes 10h 15m.
- Website
- airfrance.com
Flights from Lyon–Saint Exupéry Airport to Paris Charles De Gaulle Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €35–260
Flights from Lyon–Saint Exupéry Airport to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- €50–310
Flights from Lyon–Saint Exupéry Airport to Amsterdam Airport Schiphol via Paris Charles De Gaulle Airport
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €55–320
- Website
- brusselsairlines.com
Flights from Lyon–Saint Exupéry Airport to Brussels Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €80–260
Flights from Geneva International Airport to Brussels Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €55–210
- Website
- swiss.com
Flights from Geneva International Airport to Brussels Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- €55–210
Flights from Geneva International Airport to Brussels Airport via Zurich
- Ave. Duration
- 3h 7m
- When
- Every day
- Estimated price
- €55–210
- Website
- lufthansa.com
Flights from Lyon–Saint Exupéry Airport to Brussels Airport via Frankfurt
- Ave. Duration
- 3h 25m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- €160–750
Flights from Lyon–Saint Exupéry Airport to Amsterdam Airport Schiphol via Frankfurt
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €110–800
Flights from Lyon–Saint Exupéry Airport to Amsterdam Airport Schiphol via Munich
- Ave. Duration
- 4h 5m
- When
- Monday to Saturday
- Estimated price
- €110–1,000
- Website
- klm.com
Flights from Lyon–Saint Exupéry Airport to Brussels Airport via Amsterdam Airport Schiphol
- Ave. Duration
- 3h 10m
- When
- Monday to Saturday
- Estimated price
- €55–320
Flights from Lyon–Saint Exupéry Airport to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- €50–310
- Website
- easyjet.com
Flights from Geneva International Airport to Brussels Airport
- Ave. Duration
- 1h 17m
- When
- Monday and Friday
- Estimated price
- €50–190
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Lyon Part Dieu to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 3h 51m
- Frequency
- Hourly
- Estimated price
- €150–250
- Website
- https://www.sncf-connect.com/en-en
Train from Lyon Perrache to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 4h 16m
- Frequency
- Twice daily
- Estimated price
- €160–250
- Website
- https://www.sncf-connect.com/en-en
Train from Lyon Part Dieu to Chalon Sur Saone
- Ave. Duration
- 1h 2m
- Frequency
- Every 4 hours
- Estimated price
- €26–45
- Website
- https://www.sncf-connect.com/en-en
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- €30–55
- Website
- https://www.sncf-connect.com/en-en
Train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €65–110
- Website
- https://www.sncf-connect.com/en-en
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Lyon Part Dieu to Chalon Sur Saone
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- €21–45
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €27–55
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +44 (0)3432 186 186
- Website
- eurostar.com
Train from Aeroport Cdg2 Tgv Roissy to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 13m
- Frequency
- 6 times a week
- Estimated price
- €95–170
- Website
- https://www.eurostar.com/rw-en
Train from Schiphol Airport to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €60–110
- Website
- https://www.eurostar.com/rw-en
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Lyon to Brussels-North train station
- Ave. Duration
- 10h 15m
- Frequency
- 5 times a week
- Estimated price
- €55–95
- Website
- https://www.flixbus.co.uk
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Chalon-sur-Saône - Train Station to Brussels - Midi Train Station
- Ave. Duration
- 8h 5m
- Frequency
- Twice daily
- Estimated price
- €50–95
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +3 318 576 2228
- Website
- blablacar.com
Rideshare from Lyon to Brussels
- Ave. Duration
- 8h 31m
- Frequency
- 5 times a day
- Estimated price
- €47–48
- Schedules at
- blablacar.com
Want to know more about travelling around Belgium
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More Questions & Answers
Lyon to Brussels Central Station bus services, operated by FlixBus, arrive at Brussels-North train station.
Lyon to Brussels Central Station train services, operated by TGV inOui, arrive at Brussel-Zuid / Bruxelles-Midi station.
Yes, the driving distance between Lyon to Brussels Central Station is 664 km. It takes approximately 7h 24m to drive from Lyon to Brussels Central Station.
Book your Lyon to Brussels Central Station train tickets online with Omio.
Book your Lyon to Brussels Central Station bus tickets online with Omio.
There are 1754+ hotels available in Brussels Central Station.
Check out Blablacar's carpooling service for rideshare options between Lyon and Brussels Central Station. A great option if you don't have a driver's licence or want to avoid public transport.

























