There are 12 ways to get from Lyon to Palermo (Region) by plane, bus, train (Trenitalia), car, car ferry, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Lyon–Saint Exupéry Airport to Palermo Airport, bus
best- Fly from Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO)plane LYS - PMO
- Take the bus from Palermo to Vicaribus
7h 58mTrain to Turin Caselle Airport, fly to Catania–Fontanarossa Airport, train
cheapest- Take the train from Lyon Part Dieu to Torino Porta Susatrain
- Fly from Turin Caselle Airport (TRN) to Catania–Fontanarossa Airport (CTA)plane TRN - CTA
- Take the train from Catania Aeroporto Fontanarossa to Roccapalumba-Aliatrain
11h 19m€107–286Train
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Termini Imeresetrain Ic
21h 30m€237–409Drive, car ferry
- Drive from Lyon to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
- Drive from Port of Palermo to Palermo (Region)car
26h 36m€183–271Bus via Caserta
- Take the bus from Lyon Lyon Perrache Bus Station to Caserta Piazza Carlo Terzobus
- Take the bus from Caserta pzza Garibaldi to Palermo Terminal Busbus
- Take the bus from Palermo to Vicaribus
31h 20mTrain to Turin Caselle Airport, fly to Palermo Airport, bus
- Take the train from Lyon Part Dieu to Torino Porta Susatrain
- Fly from Turin Caselle Airport (TRN) to Palermo Airport (PMO)plane TRN - PMO
- Take the bus from Palermo to Vicaribus
10h 55mTrain to Geneva International Airport, fly to Palermo Airport, bus
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Palermo Airport (PMO)plane GVA - PMO
- Take the bus from Palermo to Vicaribus
9h 53mTrain to Geneva International Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Catania–Fontanarossa Airport (CTA)plane GVA - CTA
- Take the train from Catania Aeroporto Fontanarossa to Roccapalumba-Aliatrain
10h 27m€145–375Train, train to Milano Malpensa Airport, fly to Palermo Airport, bus
- Take the train from Lyon Part Dieu to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Palermo Airport (PMO)plane MXP - PMO
- Take the bus from Palermo to Vicaribus
12h 14mTrain to Turin Caselle Airport, fly to Trapani Airport, bus
- Take the train from Lyon Part Dieu to Torino Porta Susatrain
- Fly from Turin Caselle Airport (TRN) to Trapani Airport (TPS)plane TRN - TPS
- Take the bus from Trapani Birgi Airport to Palermo Terminal Busbus
- Take the bus from Palermo to Vicaribus
12h 27mTrain, bus
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
- Take the bus from Palermo to Vicaribus
24h 12mBus
- Take the bus from Lyon - Gerland Bus Station to Turin - Vittorio Emanuele Bus Stationbus
- Take the bus from Turin to Palermobus
- Take the bus from Palermo to Vicaribus
32h 25m
Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Lyon to Palermo (Region) is to train and fly which costs €100 - €290 and takes 11h 19m.
The fastest way to get from Lyon to Palermo (Region) is to train and fly which takes 10h 27m and costs €140 - €380.
No, there is no direct bus from Lyon station to Palermo (Region). However, there are services departing from Lyon Lyon Perrache Bus Station and arriving at Vicari via Caserta pzza Garibaldi and Palermo. The journey, including transfers, takes approximately 31h 20m.
No, there is no direct train from Lyon to Palermo (Region). However, there are services departing from Lyon Part Dieu and arriving at Roccapalumba-Alia via Milano Centrale, Roma Termini and Termini Imerese. The journey, including transfers, takes approximately 21h 30m.
The distance between Lyon and Palermo (Region) is 1177 km.
The best way to get from Lyon to Palermo (Region) without a car is to train which takes 21h 30m and costs €230 - €410.
It takes approximately 7h 58m to get from Lyon to Palermo (Region), including transfers.
Lyon to Palermo (Region) bus services, operated by Itabus S.p.A., depart from Lyon Lyon Perrache Bus Station.
Lyon to Palermo (Region) train services, operated by Trenitalia, depart from Lyon Part Dieu station.
The best way to get from Lyon to Palermo (Region) is to train which takes 21h 30m and costs €230 - €410. Alternatively, you can bus via Caserta, which costs and takes 31h 20m.
What companies run services between Lyon, France and Palermo (Region), Sicily, Italy?
You can take a train from Lyon Part Dieu to Palermo (Region) via Milano Centrale, Roma Termini, Termini Imerese, and Roccapalumba-Alia in around 21h 30m. Alternatively, you can take a bus from Lyon Lyon Perrache Bus Station to Vicari via Caserta Piazza Carlo Terzo, Caserta pzza Garibaldi, Palermo Terminal Bus, and Palermo in around 31h 20m.
- Website
- ryanair.com
Flights from Turin Caselle Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €25–200
Flights from Turin Caselle Airport to Palermo Airport via Naples
- Ave. Duration
- 3h 25m
- When
- Friday and Saturday
- Estimated price
- €25–200
Flights from Turin Caselle Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- €30–290
Flights from Turin Caselle Airport to Catania–Fontanarossa Airport via Pescara
- Ave. Duration
- 3h 40m
- When
- Friday and Sunday
- Estimated price
- €30–290
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €40–130
Flights from Milano Malpensa Airport to Palermo Airport via Naples
- Ave. Duration
- 3h 25m
- When
- Friday and Saturday
- Estimated price
- €40–130
Flights from Turin Caselle Airport to Trapani Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- €55–130
- Website
- easyjet.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 1h 50m
- When
- Saturday
- Estimated price
- €75–280
Flights from Geneva International Airport to Palermo Airport
- Ave. Duration
- 1h 50m
- When
- Thursday and Saturday
- Estimated price
- €50–310
Flights from Geneva International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- €60–210
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- €30–290
Flights from Milano Malpensa Airport to Palermo Airport via Naples
- Ave. Duration
- 3h 52m
- When
- Saturday and Friday
- Estimated price
- €30–290
- Website
- ita-airways.com
Flights from Turin Caselle Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €70–170
Flights from Geneva International Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–300
Flights from Geneva International Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €100–200
Flights from Turin Caselle Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €75–170
- Website
- volotea.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Friday
- Estimated price
- €27–250
Flights from Turin Caselle Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €70–170
Flights from Geneva International Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–300
Flights from Geneva International Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €100–200
Flights from Turin Caselle Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- €75–170
- Website
- flyulendo.com
Flights from Turin Caselle Airport to Palermo Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €10–80
Flights from Turin Caselle Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- €17–80
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €10–220
- Website
- transavia.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 2h
- When
- Friday
- Estimated price
- €50–290
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Catania Aeroporto Fontanarossa to Roccapalumba-Alia
- Ave. Duration
- 1h 58m
- Frequency
- Every 4 hours
- Estimated price
- €19–28
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Catania Aeroporto Fontanarossa to Roccapalumba-Alia
- Ave. Duration
- 1h 58m
- Frequency
- Every 4 hours
- Estimated price
- €19–28
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €35–50
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 4m
- Frequency
- Hourly
- Estimated price
- €75–130
- Website
- Trenitalia Frecce
Train from Torino Porta Susa to Roma Termini
- Ave. Duration
- 4h 45m
- Frequency
- Hourly
- Estimated price
- €95–170
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- €65–110
- Website
- Italo Treno
Train from Torino Porta Susa to Roma Termini
- Ave. Duration
- 4h 54m
- Frequency
- Hourly
- Estimated price
- €80–140
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Every 3 hours
- Estimated price
- €28–50
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Every 3 hours
- Estimated price
- €28–50
- Website
- Oui.SNCF
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- €30–50
- Website
- TGV inOui
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- €30–50
- Website
- TGV inOui
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Milano Centrale to Malpensa Aeroporto T1
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +39 091-6208000
- [email protected]
- Website
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Lyon Lyon Perrache Bus Station to Caserta Piazza Carlo Terzo
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- €65–120
- Website
- Itabus S.p.A.
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Caserta pzza Garibaldi to Palermo Terminal Bus
- Ave. Duration
- 9h 45m
- Frequency
- Twice daily
- Estimated price
- €30–45
- Schedules at
- autoservizisalemi.it
Bus from Trapani Birgi Airport to Palermo Terminal Bus
- Ave. Duration
- 1h 55m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- Autoservizi Salemi Srl
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Lyon - Gerland Bus Station to Turin - Vittorio Emanuele Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 2 hours
- Estimated price
- €22–40
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Lyon - Gerland Bus Station to Turin - Vittorio Emanuele Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Flixbus
Bus from Turin to Palermo
- Ave. Duration
- 24h 5m
- Frequency
- Once daily
- Estimated price
- €150–230
- Website
- Flixbus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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Booking & Getting There
Lyon to Palermo (Region) bus services, operated by Itabus S.p.A., arrive at Caserta Piazza Carlo Terzo station.
Lyon to Palermo (Region) train services, operated by Trenitalia, arrive at Milano Centrale station.
There are 992+ hotels available in Palermo (Region).
























































